Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Mar 23;13(3):e14065.
doi: 10.7759/cureus.14065.

Unusual Cutaneous Metastases From Colon Adenocarcinoma

Penélope Correia  1 , Joana F Correia  1 , Horácio Scigliano  2 , Mário Nora  1
Affiliations
Case Reports

Unusual Cutaneous Metastases From Colon Adenocarcinoma

Penélope Correia et al. Cureus. .

Abstract

Skin metastases from internal malignancies are rare, even more from colorectal tumours, and are usually a sign of disseminated disease with a poor prognosis. However, with increased numbers of cancer survivors, a high index of suspicion should exist during the evaluation of cutaneous lesions since it can be the initial sign of disease progression or even the first sign that triggers a malignancy diagnosis, potentially improving the patient's odds. Herein, we report a case of synchronous cutaneous metastases from colon adenocarcinoma with unusual localization on the back and forearm of a 65-year-old man.

Keywords: colorectal adenocarcinoma; cutaneous metastasis; skin metastasis.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. CT-scan images
CT-scan images compatible with sigmoid neoplasia (A); pulmonary metastasis (B); liver metastasis (C); and peritoneal carcinomatosis (D)
Figure 2
Figure 2. Nodular cutaneous lesions at the back and forearm (last one excised for analysis)
Figure 3
Figure 3. Metastatic colon adenocarcinoma involving the skin (A-D)
Haematoxylin-eosin, original magnifications x 40 (A) and x 100 (B); C: cytokeratin 20; D: CDX2 (C-D - original magnifications x 40). Note in B the presence of typical dirty necrotic debris material with karyorrhectic nuclei (black arrow).
See this image and copyright information in PMC

References

    1. Cutaneous metastasis of internal tumors. Choate E, Nobori A, Worswick S. Dermatol Clin. 2019 Oct;37:545–554. - PubMed
    1. Cutaneous metastasis of colon adenocarcinoma: a case report and review of the literature. Nesseris I, Ditsos I, Tsamakis C, et al. An Bras Dermatol. 2013;88:56–58. - PMC - PubMed
    1. Large single cutaneous metastasis of colon adenocarcinoma mimicking a squamous cell carcinoma of the skin: A case report. Faenza M, Del Torto G, Di Costanzo P, et al. Int J Surg Case Rep. 2019;56:96–100. - PMC - PubMed
    1. Cutaneous mestastases of visceral tumours: a review. Nashan D, Müller ML, Braun-Falco M, Reichenberger S, Szeimies RM, Bruckner-Tuderman L. J Cancer Res Clin Oncol. 2009;135:1–14. - PubMed
    1. Unusual cutaneous metastatic carcinoma. Ruiz S, Salihi S, Prietto V, et al. Ann Diagn Pathol. 2019;43:151399. - PubMed

Publication types

LinkOut - more resources