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. 2021 Apr 26;16(4):e0250730.
doi: 10.1371/journal.pone.0250730. eCollection 2021.

Utility of hospitalization for elderly individuals affected by COVID-19

Affiliations

Utility of hospitalization for elderly individuals affected by COVID-19

Giorgio Costantino et al. PLoS One. .

Abstract

Background: During the COVID-19 pandemic, the number of individuals needing hospital admission has sometimes exceeded the availability of hospital beds. Since hospitalization can have detrimental effects on older individuals, preference has been given to younger patients. The aim of this study was to assess the utility of hospitalization for elderly affected by COVID-19. We hypothesized that their mortality decreases when there is greater access to hospitals.

Methods: This study examined 1902 COVID-19 patients consecutively admitted to three large hospitals in Milan, Italy. Overall mortality data for Milan from the same period was retrieved. Based on emergency department (ED) data, both peak and off-peak phases were identified. The percentage of elderly patients admitted to EDs during these two phases were compared by calculating the standardized mortality ratio (SMR) of the individuals younger than, versus older than, 80 years.

Results: The median age of the patients hospitalized during the peak phase was lower than the median age during the off-peak phase (64 vs. 75 years, respectively; p <0.001). However, while the SMR for the younger patients was lower during the off-peak phase (1.98, 95% CI: 1.72-2.29 versus 1.40, 95% CI: 1.25-1.58, respectively), the SMR was similar between both phases for the elderly patients (2.28, 95% CI: 2.07-2.52 versus 2.48, 95% CI: 2.32-2.65, respectively).

Conclusions: Greater access to hospitals during an off-peak phase did not affect the mortality rate of COVID-19-positive elderly patients in Milan. This finding, if confirmed in other settings, should influence future decisions regarding resource management of health care organizations.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Number of deaths in 2020 according to age class.
White dots represent the daily deaths of patients aged ≥ 80 y, black diamonds represent the daily deaths of patients < 80 y. Solid lines represent trends among the data.

References

    1. Odone A, Delmonte D, Scognamiglio T, Signorelli C. COVID-19 deaths in Lombardy, Italy: data in context. The Lancet Public Health. Elsevier Ltd; 2020. p. e310. 10.1016/S2468-2667(20)30099-2 - DOI - PMC - PubMed
    1. Rizzo M, Foresti L, Montano N. Comparison of Reported Deaths From COVID-19 and Increase in Total Mortality in Italy. JAMA Intern Med. 2020;180: 1250. 10.1001/jamainternmed.2020.2543 - DOI - PMC - PubMed
    1. Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A, et al.. Baseline Characteristics and Outcomes of 1591 Patients Infected with SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy. JAMA—J Am Med Assoc. 2020;323: 1574–1581. 10.1001/jama.2020.5394 - DOI - PMC - PubMed
    1. Grasselli G, Pesenti A, Cecconi M. Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast during an Emergency Response. JAMA—Journal of the American Medical Association. American Medical Association; 2020. pp. 1545–1546. 10.1001/jama.2020.4031 - DOI - PubMed
    1. Jaffe E, Strugo R, Bin E, Blustein O, Rosenblat I, Alpert EA, et al.. The role of emergency medical services in containing COVID-19. American Journal of Emergency Medicine. W.B. Saunders; 2020. pp. 1526–1527. 10.1016/j.ajem.2020.04.023 - DOI - PMC - PubMed

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