. 2021 Apr 26;21(1):209.

doi: 10.1186/s12893-021-01209-z.

Septicemia and mortality after noncardiac surgery associated with CHA2DS2-VASc score: a retrospective cohort study based on a real-world database

Li-Chin Sung^{1

2

3}, Chih-Chung Liu^{4

5

6}, Chao-Shun Lin^{4

5

6}, Chun-Chieh Yeh^{7

8}, Yih-Giun Cherng^#^{6

9}, Ta-Liang Chen^{5

6

10}, Chien-Chang Liao^#^{11

12

13

14

15}

Affiliations

¹ Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan.
² Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
³ Taipei Heart Institute, Taipei Medical University, Taipei, Taiwan.
⁴ Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan.
⁵ Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan.
⁶ Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
⁷ Department of Surgery, China Medical University Hospital, Taichung, Taiwan.
⁸ Department of Surgery, University of Illinois, Chicago, USA.
⁹ Department of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
¹⁰ Department of Anesthesiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
¹¹ Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan. jacky48863027@yahoo.com.tw.
¹² Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan. jacky48863027@yahoo.com.tw.
¹³ Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. jacky48863027@yahoo.com.tw.
¹⁴ Research Center of Big Data and Meta-Analysis, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. jacky48863027@yahoo.com.tw.
¹⁵ School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan. jacky48863027@yahoo.com.tw.

^# Contributed equally.

PMID: 33902523
PMCID: PMC8073955
DOI: 10.1186/s12893-021-01209-z

Septicemia and mortality after noncardiac surgery associated with CHA2DS2-VASc score: a retrospective cohort study based on a real-world database

Li-Chin Sung et al. BMC Surg. 2021.

. 2021 Apr 26;21(1):209.

doi: 10.1186/s12893-021-01209-z.

Authors

Li-Chin Sung^{1

2

3}, Chih-Chung Liu^{4

5

6}, Chao-Shun Lin^{4

5

6}, Chun-Chieh Yeh^{7

8}, Yih-Giun Cherng^#^{6

9}, Ta-Liang Chen^{5

6

10}, Chien-Chang Liao^#^{11

12

13

14

15}

Affiliations

¹ Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei City, Taiwan.
² Division of Cardiology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
³ Taipei Heart Institute, Taipei Medical University, Taipei, Taiwan.
⁴ Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan.
⁵ Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan.
⁶ Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
⁷ Department of Surgery, China Medical University Hospital, Taichung, Taiwan.
⁸ Department of Surgery, University of Illinois, Chicago, USA.
⁹ Department of Anesthesiology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan.
¹⁰ Department of Anesthesiology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
¹¹ Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan. jacky48863027@yahoo.com.tw.
¹² Anesthesiology and Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan. jacky48863027@yahoo.com.tw.
¹³ Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. jacky48863027@yahoo.com.tw.
¹⁴ Research Center of Big Data and Meta-Analysis, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. jacky48863027@yahoo.com.tw.
¹⁵ School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan. jacky48863027@yahoo.com.tw.

^# Contributed equally.

PMID: 33902523
PMCID: PMC8073955
DOI: 10.1186/s12893-021-01209-z

Abstract

Background: Little was know about the association between the CHA2DS2-VASc score and postoperative outcomes. Our purpose is to evaluate the effects of CHA2DS2-VASc score on the perioperative outcomes in patients with atrial fibrillation (AF).

Methods: We identified 47,402 patients with AF over the age of 20 years who underwent noncardiac surgeries between 2008 and 2013 from claims data of the National Health Insurance in Taiwan. The CHA2DS2-VASc score was used to evaluate postoperative complications, mortality and the consumption of medical resources by calculating adjusted odds ratios (ORs) and 95% confidence intervals (CIs).

Results: Compared with patients with a CHA2DS2-VASc score of 0, patients with scores ≥ 5 had an increased risk of postoperative septicemia (OR 2.76, 95% CI 2.00-3.80), intensive care (OR 2.55, 95% CI 2.12-3.06), and mortality (OR 2.04, 95% CI 1.14-3.64). There was a significant positive correlation between risk of postoperative complication and the CHA2DS2-VASc score (P < 0.0001).

Conclusion: The CHA2DS2-VASc score was highly associated with postoperative septicemia, intensive care, and 30-day mortality among AF patients. Cardiologists and surgical care teams may consider using the CHA2DS2-VASc score to evaluate perioperative outcome risks in patients with AF.

Keywords: Atrial fibrillation; CHA2DS2-VASc score; Infectious complications; Mortality; Surgery.

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Conflict of interest statement

None to declare.

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Septicemia and mortality after noncardiac surgery associated with CHA2DS2-VASc score: a retrospective cohort study based on a real-world database

Affiliations

Septicemia and mortality after noncardiac surgery associated with CHA2DS2-VASc score: a retrospective cohort study based on a real-world database

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