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Comment
. 2021 Jun;17(6):309.
doi: 10.1038/s41584-021-00619-w.

Complement primes joints for inflammation

Joanna Clarke  1
Affiliations
Comment

Complement primes joints for inflammation

Joanna Clarke. Nat Rev Rheumatol. 2021 Jun.
No abstract available

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Comment on

  • The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.
    Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp SJ, Walker KI, Ackermann JA, Chen X, Turner J, Zhu H, Seyler L, Euler M, Kirchner P, Krüger R, Ekici AB, Major T, Aust O, Weidner D, Fischer A, Andes FT, Stanojevic Z, Trajkovic V, Herrmann M, Korb-Pap A, Wank I, Hess A, Winter J, Wixler V, Distler J, Steiner G, Kiener HP, Frey B, Kling L, Raza K, Frey S, Kleyer A, Bäuerle T, Hughes TR, Grüneboom A, Steffen U, Krönke G, Croft AP, Filer A, Köhl J, Klein K, Buckley CD, Schett G, Mougiakakos D, Hoffmann MH. Friščić J, et al. Immunity. 2021 May 11;54(5):1002-1021.e10. doi: 10.1016/j.immuni.2021.03.003. Epub 2021 Mar 23. Immunity. 2021. PMID: 33761330

References

Original article
    1. Friščić, J. et al. The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. Immunity https://doi.org/10.1016/j.immuni.2021.03.003 (2021) - DOI - PubMed
Related article
    1. Nygaard, G. & Firestein, G. S. Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes. Nat. Rev. Rheumatol. 16, 316–333 (2020) - DOI

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