TCF3 Dominant Negative Variant Causes an Early Block in B-Lymphopoiesis and Agammaglobulinemia

Ebtehal Al Sheikh^{1

2}, Peter D Arkwright^{3

4}, Archana Herwadkar⁵, Tracy Hussell¹, Tracy A Briggs^{1

2}

Affiliations

¹ Lydia Becker Institute of Immunology & Inflammation, University of Manchester, Manchester, M13 9XX, UK.
² Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester, M13 9WL, UK.
³ Lydia Becker Institute of Immunology & Inflammation, University of Manchester, Manchester, M13 9XX, UK. peter.arkwright@manchester.ac.uk.
⁴ Department of Paediatric Allergy & Immunology, Royal Manchester Children's Hospital, Oxford Rd, Manchester, M13 9WL, UK. peter.arkwright@manchester.ac.uk.
⁵ Department of Immunology, Salford Royal Foundation NHS Trust, Manchester, M6 8HD, UK.

Case Reports

Ebtehal Al Sheikh et al. J Clin Immunol. 2021 Aug.

. 2021 Aug;41(6):1391-1394.

doi: 10.1007/s10875-021-01049-9. Epub 2021 Apr 27.

Ebtehal Al Sheikh^{1

2}, Peter D Arkwright^{3

4}, Archana Herwadkar⁵, Tracy Hussell¹, Tracy A Briggs^{1

2}

¹ Lydia Becker Institute of Immunology & Inflammation, University of Manchester, Manchester, M13 9XX, UK.
² Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester, M13 9WL, UK.
³ Lydia Becker Institute of Immunology & Inflammation, University of Manchester, Manchester, M13 9XX, UK. peter.arkwright@manchester.ac.uk.
⁴ Department of Paediatric Allergy & Immunology, Royal Manchester Children's Hospital, Oxford Rd, Manchester, M13 9WL, UK. peter.arkwright@manchester.ac.uk.
⁵ Department of Immunology, Salford Royal Foundation NHS Trust, Manchester, M6 8HD, UK.

No abstract available

References

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