Occurrence of two histopathologically different malignancies

Abstract

Background: Synchronous primary malignancies are defined as two or more malignancies without finding a subordinate relationship in different organs of the patient. Reports of patients with primary malignancies with hepatocellular carcinoma are rare.

Case: We describe the course of the disease in a 71-year-old patient with a synchronous occurrence of two histopathologically different malignancies.

Conclusion: Consistent screening can detect individual tumors early. Understanding the clinicopathological properties and prognostic factors in synchronous malignancies is important to facilitate the treatment.

Keywords: hepatocellular carcinoma; prostate cancer; prostatic carcinoma; sorafenib; synchronous malignancies.