Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun;41(6):e369-e378.
doi: 10.1161/ATVBAHA.121.316035. Epub 2021 Apr 29.

Soluble CD14 Levels in the Jackson Heart Study: Associations With Cardiovascular Disease Risk and Genetic Variants

Affiliations

Soluble CD14 Levels in the Jackson Heart Study: Associations With Cardiovascular Disease Risk and Genetic Variants

Maggie A Stanislawski et al. Arterioscler Thromb Vasc Biol. 2021 Jun.

Abstract

[Figure: see text].

Keywords: cardiovascular disease; genetics; heart failure; inflammation; risk.

PubMed Disclaimer

Figures

Figure 1:
Figure 1:
Locus-Zoom plot of chromosome 5q31 for association with sCD14 in unconditional single variant analyses showing top result, rs75652866 (Chr5:140633846).

References

    1. Granucci F, Zanoni I. Role of CD14 in host protection against infections and in metabolism regulation. Front Cell Infect Microbiol. 2013;3. doi:10.3389/fcimb.2013.00032 - DOI - PMC - PubMed
    1. Poesen R, Ramezani A, Claes K, Augustijns P, Kuypers D, Barrows IR, Muralidharan J, Evenepoel P, Meijers B, Raj DS. Associations of Soluble CD14 and Endotoxin with Mortality, Cardiovascular Disease, and Progression of Kidney Disease among Patients with CKD. CJASN. 2015;10:1525–1533. doi:10.2215/CJN.03100315 - DOI - PMC - PubMed
    1. Fernández-Real JM, Pulgar SP del, Luche E, Moreno-Navarrete JM, Waget A, Serino M, Sorianello E, Sánchez-Pla A, Pontaque FC, Vendrell J, Chacón MR, Ricart W, Burcelin R, Zorzano A. CD14 Modulates Inflammation-Driven Insulin Resistance. Diabetes. 2011;60:2179–2186. doi:10.2337/db10-1210 - DOI - PMC - PubMed
    1. Reiner Alex P, Lange Ethan M, Jenny Nancy S, Chaves Paulo HM, Ellis Jaclyn, Li Jin, Walston Jeremy, Lange Leslie A, Cushman Mary, Tracy Russell P. Soluble CD14. Arteriosclerosis, Thrombosis, and Vascular Biology. 2013;33:158–164. doi:10.1161/ATVBAHA.112.300421 - DOI - PMC - PubMed
    1. Cushman M, McClure LA, Howard VJ, Jenny NS, Lakoski SG, Howard G. Implications of Elevated C-reactive Protein for Cardiovascular Risk Stratification in Black and White Men and Women in the United States. Clin Chem. 2009;55:1627–1636. doi:10.1373/clinchem.2008.122093 - DOI - PMC - PubMed

Publication types

MeSH terms