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. 1977 Dec 8;270(5637):486-94.
doi: 10.1038/270486a0.

Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone

P H Seeburg, J Shine, J A Martial, J D Baxter, H M Goodman

Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone

P H Seeburg et al. Nature. .

Abstract

The primary structure of DNA containing the sequence for rat pituitary growth hormone mRNA has been determined. DNA was obtained by reverse transcription of polyadenylated RNA from cultured pituitary cells and from recombinant bacterial plasmids. The amino acid sequences for rat growth hormone and its precursor form have been deduced from the determined nucleotide sequences.

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