Novel insights into liver homeostasis and regeneration

Affiliations

Comment

George K Michalopoulos. Nat Rev Gastroenterol Hepatol. 2021 Jun.

. 2021 Jun;18(6):369-370.

doi: 10.1038/s41575-021-00454-0.

¹ Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. michalopoulosgk@upmc.edu.

No abstract available

Comment on

Liver homeostasis is maintained by midlobular zone 2 hepatocytes.
Wei Y, Wang YG, Jia Y, Li L, Yoon J, Zhang S, Wang Z, Zhang Y, Zhu M, Sharma T, Lin YH, Hsieh MH, Albrecht JH, Le PT, Rosen CJ, Wang T, Zhu H. Wei Y, et al. Science. 2021 Feb 26;371(6532):eabb1625. doi: 10.1126/science.abb1625. Science. 2021. PMID: 33632817 Free PMC article.
Proliferation tracing reveals regional hepatocyte generation in liver homeostasis and repair.
He L, Pu W, Liu X, Zhang Z, Han M, Li Y, Huang X, Han X, Li Y, Liu K, Shi M, Lai L, Sun R, Wang QD, Ji Y, Tchorz JS, Zhou B. He L, et al. Science. 2021 Feb 26;371(6532):eabc4346. doi: 10.1126/science.abc4346. Science. 2021. PMID: 33632818
Cellular plasticity balances the metabolic and proliferation dynamics of a regenerating liver.
Chembazhi UV, Bangru S, Hernaez M, Kalsotra A. Chembazhi UV, et al. Genome Res. 2021 Apr;31(4):576-591. doi: 10.1101/gr.267013.120. Epub 2021 Mar 1. Genome Res. 2021. PMID: 33649154 Free PMC article.

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