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Case Reports
. 2021 Mar 18;52(1):e7014577.
doi: 10.25100/cm.v52i1.4577.

Pityriasis rubra pilaris post-infection due COVID-19: case report

Franklin R Aguilar-Gamboa  1 , Dennis Cubas-Alarcon  2 , Miguel Villegas-Chiroque  3 , Virgilio E Failoc-Rojas  4
Affiliations
Case Reports

Pityriasis rubra pilaris post-infection due COVID-19: case report

Franklin R Aguilar-Gamboa et al. Colomb Med (Cali). .

Abstract
in English, Spanish

Case description: 32-month-old boy, IgG positive for SARS-CoV-2, presented to the emergency department with dermatologic lesions.

Clinical findings: Four days before admission, he presented skin eruptions with redness and pruritus on hands and feet. Generalized papular erythema was evidenced, upper extremities with diffuse erythematosquamous plaques, palmoplantar keratoderma, so he was evaluated by a dermatologist who diagnosed pityriasis rubra pilaris.

Treatment and outcome: rehydrating cream, cetirizine 0.5 mg/kg/day every two days, and prednisolone 2 mg/kg/day in the morning. He was discharged after 14 days, the patient presented clinical improvement, but the erythematous lesion persisted on the trunk and extremities. In the evaluation, after three months, the patient did not show the described lesions, evidencing an improvement and clinical resolution of the dermatological problems.

Clinical relevance: We report a patient with pityriasis rubra piloris associated with a post-infection by SARS-CoV-2 that had not been described before.

Descripción del caso:: Niño 32 meses de vida, con IgG positivo para SARS-CoV-2, acude al servicio de emergencia por presentar lesiones dermatológicas.

Hallazgos clínicos:: Cuatro días antes del ingreso presentó erupciones en la piel, con enrojecimiento y prurito en manos y pies. Se evidenció eritema papular generalizado, extremidades superiores con placas eritematoescamosas difusas, queratodermia palmo-plantar por lo que es evaluado por dermatólogo quien diagnostica pitiriasis rubra pilaris.

Tratamiento y resultado:: Crema rehidratantes, cetirizina 0.5 mg/kg/día cada 2 días y prednisolona 2 mg/kg/día por la mañana. Fue dado de alta a los 14 días, el paciente presenta mejora clínica, pero aún persiste la lesión eritematosa en tronco y extremidades. En la evaluación a los tres meses el paciente no mostró las lesiones descritas, evidenciando una mejoría y resolución clínica de los problemas dermatológicos.

Relevancia clínica:: Se reporta un paciente con afectación por pitiriasis rubra piloris asociado a una post-infección por SARS-CoV-2 que no se había descrito antes.

Keywords: COVID-19; SARS-CoV-2; dermatology; eczema; erythema multiforme; exanthema; keratoderma palmoplantar; pityriasis rubra pilaris; pruritus; urticaria.

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Conflict of interest statement

Conflict of interest: The authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1. Manifestations of Pityriasis rubra pilaris post-infection with COVID-19 . A. Generalized papular erythema, visible on the abdomen B. upper extremities with diffuse erythematous scaly plaques C and D. Erythematous and scaly papules involving palms and feet describing palmoplantar keratoderma and lamellar hyperkeratosis on hands and feet. The evolution was cephalo-caudal
Figura 1
Figura 1. Manifestaciones de Pitiriasis rubra pilaris ´post-infección por COVID-19. A. Eritema papular generalizado, visible en abdomen B. extremidades superiores con placas eritematoescamosas difusas C y D. Pápulas eritematosas y descamativas que comprometen palma de manosy pies lo que describe la queratodermia palmo-plantar y la hiperqueratosis laminar en manos y pies. La evolución fue cefalo-caudal
See this image and copyright information in PMC

References

    1. 1. Ellul MA, Benjamin L, Singh B, Lant S, Michael BD, Easton A, et al. Neurological associations of COVID-19. Lancet Neurology. 2020;19(9):p767-83. Doi: 10.1016/S1474-4422(20)30221-0. - PMC - PubMed
    2. Ellul MA, Benjamin L, Singh B, Lant S, Michael BD, Easton A. Neurological associations of COVID-19. Lancet Neurology. 2020;19(9):p767–p783. doi: 10.1016/S1474-4422(20)30221-0. - DOI - PMC - PubMed
    1. 2. Marazuela M, Giustina A, Puig-Domingo M. Endocrine and metabolic aspects of the COVID-19 pandemic. Rev Endocr Metab Disord. 2020;21(4):495-507. doi: 10.1007/s11154-020-09569-2 - PMC - PubMed
    2. Marazuela M, Giustina A, Puig-Domingo M. Endocrine and metabolic aspects of the COVID-19 pandemic. Rev Endocr Metab Disord. 2020;21(4):495–507. doi: 10.1007/s11154-020-09569-2. - DOI - PMC - PubMed
    1. 3. Pirzada A, Mokhtar AT, Moeller AD. COVID-19 and myocarditis: what do we know so far? CJC Open. 2020;2(4):278-85. doi: 10.1016/j.cjco.2020.05.005 - PMC - PubMed
    2. Pirzada A, Mokhtar AT, Moeller AD. COVID-19 and myocarditis what do we know so far? CJC Open. 2020;2(4):278–285. doi: 10.1016/j.cjco.2020.05.005. - DOI - PMC - PubMed
    1. 4. Carfì A, Bernabei R, Landi F. Persistent symptoms in patients after acute COVID-19. JAMA. 2020; 324(6): 603-605. doi: 10.1001/jama.2020.12603 - PMC - PubMed
    2. Carfì A, Bernabei R, Landi F. Persistent symptoms in patients after acute COVID-19. JAMA. 2020;324(6):603–605. doi: 10.1001/jama.2020.12603. - DOI - PMC - PubMed
    1. 5. Darlenski R, Tsankov N. COVID-19 pandemic and the skin: what should dermatologists know? Clin Dermatol. 2020; 38(6): 785-787. doi: 10.1016/j.clindermatol.2020.03.012 - PMC - PubMed
    2. Darlenski R, Tsankov N. COVID-19 pandemic and the skin what should dermatologists know? Clin Dermatol. 2020;38(6):785–787. doi: 10.1016/j.clindermatol.2020.03.012. - DOI - PMC - PubMed

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