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Case Reports
. 2021 May;69(5):1319-1321.
doi: 10.4103/ijo.IJO_52_21.

COVID-19 related multi-inflammatory syndrome presenting with uveitis - A case report

I K Karthika  1 , Krishna Mohan Gulla  1 , Joseph John  1 , Amit Kumar Satapathy  1 , Suchanda Sahu  2 , Bijayini Behera  3 , Priyadarshini Mishra  4
Affiliations
Case Reports

COVID-19 related multi-inflammatory syndrome presenting with uveitis - A case report

I K Karthika et al. Indian J Ophthalmol. 2021 May.

Abstract

Multi Inflammatory Syndrome (MIS-C) associated with Corona Virus Disease (COVID) in children and young adults presents with a varied clinical spectrum; from that mimicking Kawasaki disease (KD), Incomplete Kawasaki disease to even Hemophagocytic Lymphohistiocytosis. A 14-year-old girl, presented to us, with headache, fever, bilateral uveitis, unilateral cervical lymphadenopathy, oral mucosal changes and abdominal pain. A disproportionate increase in inflammatory markers and Interleukin - 6, in the setting of a negative COVID real-time reverse transcription polymerase chain reaction (RTPCR) and significantly elevated COVID antibody titre confirmed our diagnosis. She was treated with intravenous Immunoglobulin and oral steroids with which she recovered. We want to highlight considering the possibility of MIS-C in children presenting with uveitis at a time when COVID-19 has been conquering the world with community spread.

Keywords: COVID-19 in children; multi-inflammatory syndrome related to COVID-19; uveitis.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
MRI brain with orbit showing normal ONSD (a) and no evidence of demyelination (b)
Figure 2
Figure 2
Trend of inflammatory markers and response to treatment
See this image and copyright information in PMC

References

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Publication types

Supplementary concepts