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Review
. 2021 Sep;46(9):4226-4237.
doi: 10.1007/s00261-021-03089-6. Epub 2021 Apr 29.

Atypical and uncommon CT and MR imaging presentations of pancreatic ductal adenocarcinoma

Xu Hua Gong  1 , Jian Rong Xu  1 , Li Jun Qian  2
Affiliations
Review

Atypical and uncommon CT and MR imaging presentations of pancreatic ductal adenocarcinoma

Xu Hua Gong et al. Abdom Radiol (NY). 2021 Sep.

Abstract

Pancreatic ductal adenocarcinomas (PDACs) occasionally have atypical and uncommon imaging presentations that can present a diagnostic dilemma and result in false interpretation. This article aimed to illustrate these CT and MR imaging findings, including isoattenuating PDAC, coexisting acute pancreatitis, PDAC with a cystic feature, groove PDAC, diffuse PDAC, hypointensity on diffusion-weighted imaging (DWI), multifocal PDAC, intratumoral calcification, and extrapancreatic invasion with a barely discernable mass. A subset of PDACs with atypical features are occasionally encountered during routine clinical practice. Knowledge of and attention to these atypical and uncommon variable imaging features may allow radiologists to avoid misinterpretation and a delayed diagnosis.

Keywords: CT; Imaging; MR; Pancreatic ductal adenocarcinoma.

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References

    1. Al-Hawary MM, Francis IR, Chari ST, Fishman EK, Hough DM, Lu DS, et al. Pancreatic Ductal Adenocarcinoma Radiology Reporting Template: Consensus Statement of the Society of Abdominal Radiology and the American Pancreatic Association. Radiology. 2014;270(1):248-60. https://doi.org/10.1148/radiol.13131184 . - DOI - PubMed
    1. National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology. Pancreatic Adenocarcinoma. Version 2.2021. https://www.nccn.org/professionals/physician_gls/pdf/pancreatic.pdf (2021). Accessed Mar 23, 2021.
    1. Kim JH, Park SH, Yu ES, Kim MH, Kim J, Byun JH, et al. Visually isoattenuating pancreatic adenocarcinoma at dynamic-enhanced CT: frequency, clinical and pathologic characteristics, and diagnosis at imaging examinations. Radiology. 2010;257(1):87-96. https://doi.org/10.1148/radiol.10100015 . - DOI - PubMed
    1. Prokesch RW, Chow LC, Beaulieu CF, Bammer R, Jeffrey RB, Jr. Isoattenuating pancreatic adenocarcinoma at multi-detector row CT: secondary signs. Radiology. 2002;224(3):764-8. https://doi.org/10.1148/radiol.2243011284 . - DOI - PubMed
    1. Ishigami K, Yoshimitsu K, Irie H, Tajima T, Asayama Y, Nishie A, et al. Diagnostic value of the delayed phase image for iso-attenuating pancreatic carcinomas in the pancreatic parenchymal phase on multidetector computed tomography. European journal of radiology. 2009;69(1):139-46. https://doi.org/10.1016/j.ejrad.2007.09.012 . - DOI - PubMed

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