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Review
. 2021 Jun;11(3):833-844.
doi: 10.1007/s13555-021-00536-6. Epub 2021 Apr 29.

Genital and Inverse/Intertriginous Psoriasis: An Updated Review of Therapies and Recommendations for Practical Management

Julie J Hong  1 , Megan L Mosca  2 , Edward K Hadeler  2 , Nicholas D Brownstone  2 , Tina Bhutani  2 , Wilson J Liao  2
Affiliations
Review

Genital and Inverse/Intertriginous Psoriasis: An Updated Review of Therapies and Recommendations for Practical Management

Julie J Hong et al. Dermatol Ther (Heidelb). 2021 Jun.

Abstract

Genital and inverse psoriasis can develop in more than one-third of patients who have psoriasis. Psoriatic plaques in the genital and intertriginous skin are challenging to treat because the skin is thin and often occluded, making it more sensitive to certain therapies. Traditional guidelines indicate topical therapies, such as corticosteroids, topical calcineurin inhibitors (TCI), and vitamin D analogs as first-line recommendation in treating genital and inverse psoriasis. There have been developments in the treatment of genital and inverse psoriasis using systemic therapies, including IL-17 inhibitors and PDE-4 inhibitors.

Keywords: Genital; Intertriginous; Inverse; Psoriasis; Special site psoriasis.

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Figures

Fig. 1
Fig. 1
Genital and inverse psoriasis: study method for article inclusion and exclusion
Fig. 2
Fig. 2
Treatment of genital/inverse psoriasis. IL interleukin, PDE phosphodiesterase
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