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. 2021 Apr 23;13(5):739.
doi: 10.3390/v13050739.

First Report of Phodopus sungorus Papillomavirus Type 1 Infection in Roborovski Hamsters (Phodopus roborovskii)

Grega Gimpelj Domjanič  1 , Lea Hošnjak  1 , Maja M Lunar  1 , Lucijan Skubic  1 , Tomaž Mark Zorec  1 , Joško Račnik  2 , Blaž Cigler  3 , Mario Poljak  1
Affiliations

First Report of Phodopus sungorus Papillomavirus Type 1 Infection in Roborovski Hamsters (Phodopus roborovskii)

Grega Gimpelj Domjanič et al. Viruses. .

Abstract

Papillomaviruses (PVs) are considered highly species-specific with cospeciation as the main driving force in their evolution. However, a recent increase in the available PV genome sequences has revealed inconsistencies in virus-host phylogenies, which could be explained by adaptive radiation, recombination, host-switching events and a broad PV host range. Unfortunately, with a relatively low number of animal PVs characterized, understanding these incongruities remains elusive. To improve knowledge of biology and the spread of animal PV, we collected 60 swabs of the anogenital and head and neck regions from a healthy colony of 30 Roborovski hamsters (Phodopus roborovskii) and detected PVs in 44/60 (73.3%) hamster samples. This is the first report of PV infection in Roborovski hamsters. Moreover, Phodopus sungorus papillomavirus type 1 (PsuPV1), previously characterized in Siberian hamsters (Phodopus sungorus), was the only PV detected in Roborovski hamsters. In addition, after a detailed literature search, review and summary of published evidence and construction of a tanglegram linking the cladograms of PVs and their hosts, our findings were discussed in the context of available knowledge on PVs described in at least two different host species.

Keywords: Phodopus roborovskii; Phodopus sungorus papillomavirus type 1 (PsuPV1); evolution; molecular analysis; papillomavirus; phylogenetic analysis; viral cross-species transmission.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

Figures

Figure 1
Figure 1
Tanglegram linking the cladograms of papillomaviruses (PVs) and their hosts. Different clade colors indicate the respective host order. Gray lines connect PVs with their original hosts, and colored lines link the corresponding PV cross-Scheme 700. are shown.
See this image and copyright information in PMC

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