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Review
. 2021 Apr 24;26(9):2495.
doi: 10.3390/molecules26092495.

The Role of Resveratrol in Human Male Fertility

Laura M Mongioì  1 , Sarah Perelli  1 , Rosita A Condorelli  1 , Federica Barbagallo  1 , Andrea Crafa  1 , Rossella Cannarella  1 , Sandro La Vignera  1 , Aldo E Calogero  1
Affiliations
Review

The Role of Resveratrol in Human Male Fertility

Laura M Mongioì et al. Molecules. .

Abstract

Resveratrol (RSV) (3,4',5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer's disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa.

Keywords: cryopreservation; human male fertility; resveratrol; sperm parameters.

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Conflict of interest statement

The authors declare no conflict of interest

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