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Review
. 2021 Apr 16;11(4):349.
doi: 10.3390/life11040349.

Definition of Sarcopenia in Chronic Liver Disease

Seong Wan Son  1 , Do Seon Song  1 , U Im Chang  1 , Jin Mo Yang  1
Affiliations
Review

Definition of Sarcopenia in Chronic Liver Disease

Seong Wan Son et al. Life (Basel). .

Abstract

Sarcopenia, which is characterized by decline in muscle mass, muscle strength, and physical performance, is common in patients with chronic liver disease (CLD) and is associated with poor clinical outcomes. Several consensus definitions for community-dwelling elderly people have been proposed, and these recommend the use of various tools and tests to assess muscle properties and performance. These measurement tools have also been applied in patients with CLD and have been useful for predicting prognosis. However, sarcopenia and its diagnostic criteria specific to patients with CLD have not yet been clearly defined. In addition, fluid retention and body composition should be considered when sarcopenia is assessed in patients with CLD. This review aims to introduce definitions of sarcopenia and diagnostic tools used in patients with CLD.

Keywords: chronic liver disease; cutoff; definition; muscle strength; sarcopenia; skeletal muscle.

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Conflict of interest statement

We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, and there is no professional or other personal interest of any nature or kind in any product, service, and/or company.

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