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. 2021 Apr 27;9(5):49.
doi: 10.3390/dj9050049.

Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children

Huong Thi Thu Nguyen  1 , Dung Chi Vu  2 , Duc Minh Nguyen  1   3 , Quang Dinh Dang  4 , Van Khanh Tran  5 , Hung Le  6 , Son Minh Tong  1
Affiliations

Dentinogenesis Imperfecta and Caries in Osteogenesis Imperfecta among Vietnamese Children

Huong Thi Thu Nguyen et al. Dent J (Basel). .

Abstract

Osteogenesis imperfecta (OI) is a genetic disorder characterized by increased bone fragility and low bone mass, caused mainly by mutations in collagen type I encoding genes. The current study aimed to evaluate dentinogenesis imperfecta (DI), oral manifestations and caries status of OI children. Sixty-eight children (41 males, 27 females) aged from 3 to 17 years old (mean 9 ± 4.13) participated in the study. Participants were classified into three OI type groups (I-2 cases, III-31 cases and IV-35 cases). Clinical examination and an orthopantomogram were used to obtain prevalences and associations of DI, caries status, malocclusion, crossbite, open bite, eruption, impaction and missing teeth with OI. The prevalence of DI among OI patients was 47.1%, more common in OI type III than type IV. The yellow-brown discoloration type was more vulnerable to attrition than the opalescent-grey one in the primary dentition. OI seemed not to have a high risk of caries; the prevalence of caries was 69.1%. A high incidence of malocclusion, crossbite and open bite was observed. In-depth oral information would provide valuable data for better dental management in OI patients. Parents and general doctors should pay more attention to dental care to prevent caries and premature tooth loss.

Keywords: caries; dentinogenesis imperfecta; osteogenesis imperfecta.

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
Tooth discoloration in DI patients: (a) yellow-brown discoloration in primary teeth; (b) opalescent-gray discoloration in primary teeth; (c) yellow-brown discoloration in permanent teeth; (d) opalescent-gray discoloration in permanent teeth.
Figure 2
Figure 2
Pulp obliteration, low mineralization density, short roots, bulbous crowns, cervical constriction in panoramic radiography.
See this image and copyright information in PMC

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