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. 2021 Apr 29;21(1):397.
doi: 10.1186/s12879-021-06105-8.

Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital

Nan-Hui Zhang #  1 , Yi-Chun Cheng #  1 , Ran Luo  1 , Chun-Xiu Zhang  1 , Shu-Wang Ge  2 , Gang Xu  3
Affiliations

Recovery of new-onset kidney disease in COVID-19 patients discharged from hospital

Nan-Hui Zhang et al. BMC Infect Dis. .

Abstract

Background: Coronavirus disease 2019 (COVID-19) has emerged as a major global health threat with a great number of deaths worldwide. Despite abundant data on that many COVID-19 patients also displayed kidney disease, there is limited information available about the recovery of kidney disease after discharge.

Methods: Retrospective and prospective cohort study to patients with new-onset kidney disease during the COVID-19 hospitalization, admitted between January 28 to February 26, 2020. The median follow-up was 4 months after discharge. The follow-up patients were divided into the recovery group and non-recovery group. Descriptive statistics and between-groups comparison were used.

Results: In total, 143 discharged patients with new-onset kidney disease during the COVID-19 hospitalization were included. Patients had a median age was 64 (IQR, 51-70) years, and 59.4% of patients were men. During 4-months median follow-up, 91% (130 of 143) patients recovered from kidney disease, and 9% (13 of 143) patients haven't recovered. The median age of patients in the non-recovery group was 72 years, which was significantly higher than the median age of 62 years in the recovery group. Discharge serum creatinine was significantly higher in the non-recovery group than in the recovery group.

Conclusions: Most of the new-onset kidney diseases during hospitalization of COVID-19 patients recovered 4 months after discharge. We recommend that COVID-19 patients with new-onset kidney disease be followed after discharge to assess kidney recovery, especially elderly patients or patients with high discharge creatinine.

Keywords: COVID-19; Kidney disease; Renal recovery.

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Conflict of interest statement

All authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Flow chart of the selection of eligible subjects
See this image and copyright information in PMC

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