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Review
. 2021 May;31(2):119-128.
doi: 10.1016/j.thorsurg.2021.01.003.

Analysis of Recent Literature on Lung Volume Reduction Surgery

Daniel P McCarthy  1 , Lauren J Taylor  2 , Malcolm M DeCamp  3
Affiliations
Review

Analysis of Recent Literature on Lung Volume Reduction Surgery

Daniel P McCarthy et al. Thorac Surg Clin. 2021 May.

Abstract

Publication of the National Emphysema Treatment Trial (NETT) in 2003 established lung volume reduction surgery (LVRS) as a viable treatment of select patients with moderate to severe emphysema, and the only intervention since the availability of ambulatory supplemental oxygen to improve survival. Despite these findings, surgical treatment has been underused in part because of concern for high morbidity and mortality. This article reviews recent literature generated since the original NETT publication, focusing on physiologic implications of LVRS, recent data regarding the safety and durability of LVRS, and patient selection and extension of NETT criteria to other patient populations.

Keywords: COPD; Emphysema; Lung volume reduction surgery.

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Conflict of interest statement

Disclosure Dr D.P. McCarthy receives research support from Ethicon Inc and Intuitive Surgical. Dr L.J. Taylor and Dr M.M. DeCamp do not have any commercial or financial conflicts of interest.

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