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. 2021 Apr;26(17):2100420.
doi: 10.2807/1560-7917.ES.2021.26.17.2100420.

Effectiveness of the Comirnaty (BNT162b2, BioNTech/Pfizer) vaccine in preventing SARS-CoV-2 infection among healthcare workers, Treviso province, Veneto region, Italy, 27 December 2020 to 24 March 2021

Massimo Fabiani  1 , Mauro Ramigni  2 , Valentina Gobbetto  2 , Alberto Mateo-Urdiales  1   3 , Patrizio Pezzotti  1 , Cinzia Piovesan  2
Affiliations

Effectiveness of the Comirnaty (BNT162b2, BioNTech/Pfizer) vaccine in preventing SARS-CoV-2 infection among healthcare workers, Treviso province, Veneto region, Italy, 27 December 2020 to 24 March 2021

Massimo Fabiani et al. Euro Surveill. 2021 Apr.

Abstract

Data on effectiveness of the BioNTech-/Pfizer COVID-19 vaccine in real-world settings are limited. In a study of 6,423 healthcare workers in Treviso Province, Italy, we estimated that, within the time intervals of 14-21 days from the first and at least 7 days from the second dose, vaccine effectiveness in preventing SARS-CoV-2 infection was 84% (95% confidence interval (CI): 40-96) and 95% (95% CI: 62-99), respectively. These results could support the ongoing vaccination campaigns by providing evidence for targeted communication.

Keywords: COVID-19 disease; Italy; SARS-CoV-2 infection; healthcare workers; vaccine effectiveness.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Kaplan–Meier failure curves of healthcare workers by COVID-19 vaccination status, Treviso province, Italy, 3 January–24 March 2021 (n = 6,331)a
Figure 2
Figure 2
Trend of COVID-19-associated hospital admissions in the study area (n = 883,522 residents), and immunisation rate and number of SARS-CoV-2 infections among healthcare workers (n = 6,423), Treviso province, Italy, 27 December 2020–23 March 2021
See this image and copyright information in PMC

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