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. 2021 May 1;116(5):1072-1076.
doi: 10.14309/ajg.0000000000001121.

International Trends in Esophageal Squamous Cell Carcinoma and Adenocarcinoma Incidence

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International Trends in Esophageal Squamous Cell Carcinoma and Adenocarcinoma Incidence

Harriet Rumgay et al. Am J Gastroenterol. .

Abstract

Introduction: We aimed to improve our understanding of the epidemiology of squamous cell carcinoma and adenocarcinoma of the esophagus.

Methods: We estimated average annual percent change and analyzed age-period-cohort trends on population-based cancer data.

Results: We found decreases in squamous cell carcinoma incidence in half of male populations (largest decrease in US black males [average annual percent change -7.6]) and increases in adenocarcinoma incidence in nearly a third of populations. Trends may be associated with a mix of birth cohort and period effects.

Discussion: More complete data and evidence are needed to conclude the reasons for the observed trends (see Visual Abstract, Supplementary Digital Content 4, http://links.lww.com/AJG/B823).

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