Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla

Polina Kameneva¹, Artem V Artemov², Maria Eleni Kastriti¹, Erik Sundström³, Peter V Kharchenko⁴, Igor Adameyko⁵

Affiliations

¹ Department of Physiology and Pharmacology, Karolinska Institutet, Solna 17164, Sweden; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Vienna 1090, Austria.
² Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Vienna 1090, Austria.
³ Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 17164 Solna, Sweden.
⁴ Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address: peter_kharchenko@hms.harvard.edu.
⁵ Department of Physiology and Pharmacology, Karolinska Institutet, Solna 17164, Sweden; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Vienna 1090, Austria. Electronic address: igor.adameyko@ki.se.

PMID: 33930313
DOI: 10.1016/j.ccell.2021.04.009

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Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla

Polina Kameneva et al. Cancer Cell. 2021.

Free article

. 2021 May 10;39(5):590-591.

doi: 10.1016/j.ccell.2021.04.009. Epub 2021 Apr 29.

Authors

Polina Kameneva¹, Artem V Artemov², Maria Eleni Kastriti¹, Erik Sundström³, Peter V Kharchenko⁴, Igor Adameyko⁵

Affiliations

¹ Department of Physiology and Pharmacology, Karolinska Institutet, Solna 17164, Sweden; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Vienna 1090, Austria.
² Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Vienna 1090, Austria.
³ Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 17164 Solna, Sweden.
⁴ Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address: peter_kharchenko@hms.harvard.edu.
⁵ Department of Physiology and Pharmacology, Karolinska Institutet, Solna 17164, Sweden; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Vienna 1090, Austria. Electronic address: igor.adameyko@ki.se.

PMID: 33930313
DOI: 10.1016/j.ccell.2021.04.009

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Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma.
Dong R, Yang R, Zhan Y, Lai HD, Ye CJ, Yao XY, Luo WQ, Cheng XM, Miao JJ, Wang JF, Liu BH, Liu XQ, Xie LL, Li Y, Zhang M, Chen L, Song WC, Qian W, Gao WQ, Tang YH, Shen CY, Jiang W, Chen G, Yao W, Dong KR, Xiao XM, Zheng S, Li K, Wang J. Dong R, et al. Cancer Cell. 2020 Nov 9;38(5):716-733.e6. doi: 10.1016/j.ccell.2020.08.014. Epub 2020 Sep 17. Cancer Cell. 2020. PMID: 32946775

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Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla

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Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla

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