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Editorial
. 2021 Aug;160(2):e161-e164.
doi: 10.1016/j.chest.2021.04.043. Epub 2021 Apr 27.

Does Endothelial Vulnerability in OSA Syndrome Promote COVID-19 Encephalopathy?

Gautier Breville  1 , Dan Adler  2 , Marjolaine Uginet  3 , Frederic Assal  3 , Renaud Tamisier  4 , Patrice H Lalive  5 , Jean-Louis Pepin  6 , Gilles Allali  7
Affiliations
Editorial

Does Endothelial Vulnerability in OSA Syndrome Promote COVID-19 Encephalopathy?

Gautier Breville et al. Chest. 2021 Aug.
No abstract available

Keywords: COVID-19; OSA syndrome; SARS-CoV2; encephalopathy.

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Figures

Figure 1
Figure 1
Immune system modulation and endothelial changes of the blood-brain barrier and the blood-air barrier comparison of OSA syndrome and COVID-19-related encephalopathy. ACE2 = angiotensin-converting enzyme-2; GCSF = granulocyte colony-stimulating factor; ICAM1 = intercellular adhesion molecule–1; IFNγ = interferon gamma; IP-10 = interferon gamma-inducible protein (IP) 10 or CXCL10; MCP-1 = monocyte chemoattractant protein-1 (or CCL2); MIP-1a = macrophage inflammatory protein 1-alpha; OSAS = OSA syndrome; TNFα = tumor necrosis factor alpha.
Figure 2
Figure 2
Immune system changes and endothelium dysfunction in both OSA syndrome and COVID-19. NF- κB = nuclear factor kB; OSAS = OSA syndrome.
See this image and copyright information in PMC

References

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