Immune response to SARS-CoV-2 infection and vaccination in patients receiving kidney replacement therapy
- PMID: 33931226
- PMCID: PMC8055920
- DOI: 10.1016/j.kint.2021.04.007
Immune response to SARS-CoV-2 infection and vaccination in patients receiving kidney replacement therapy
Abstract
In this issue of Kidney International, the initial experience regarding the immunogenicity of prior coronavirus disease 2019 (COVID-19) infection and the response to the COVID-19 vaccines among patients on maintenance dialysis and kidney transplant recipients is summarized. Preliminary data suggest that there is durability of immune response after COVID-19 infection. Although immune response to the first dose of vaccine is less in infection-naïve patients than healthy individuals in both groups, after the second vaccine dose a significant portion of patients receiving maintenance dialysis develop robust antibody titers, whereas kidney transplant recipients show a less-strong immune response.
Copyright © 2021 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.
Comment in
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Gross hematuria following vaccination for severe acute respiratory syndrome coronavirus 2 in 2 patients with IgA nephropathy.Kidney Int. 2021 Jun;99(6):1487. doi: 10.1016/j.kint.2021.03.002. Epub 2021 Mar 24. Kidney Int. 2021. PMID: 33771584 Free PMC article. No abstract available.
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Weak anti-SARS-CoV-2 antibody response after the first injection of an mRNA COVID-19 vaccine in kidney transplant recipients.Kidney Int. 2021 Jun;99(6):1487-1489. doi: 10.1016/j.kint.2021.03.014. Epub 2021 Mar 26. Kidney Int. 2021. PMID: 33775674 Free PMC article. No abstract available.
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Low immunization rates among kidney transplant recipients who received 2 doses of the mRNA-1273 SARS-CoV-2 vaccine.Kidney Int. 2021 Jun;99(6):1498-1500. doi: 10.1016/j.kint.2021.04.005. Epub 2021 Apr 20. Kidney Int. 2021. PMID: 33887315 Free PMC article. No abstract available.
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Neutralizing SARS-CoV-2 antibody response in dialysis patients after the first dose of the BNT162b2 mRNA COVID-19 vaccine: the war is far from being won.Kidney Int. 2021 Jun;99(6):1494-1496. doi: 10.1016/j.kint.2021.04.010. Epub 2021 Apr 20. Kidney Int. 2021. PMID: 33887320 Free PMC article. No abstract available.
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Reasons for COVID-19 vaccination hesitancy in hemodialysis patients.Kidney Int. 2021 Sep;100(3):702. doi: 10.1016/j.kint.2021.07.003. Epub 2021 Jul 10. Kidney Int. 2021. PMID: 34256055 Free PMC article. No abstract available.
References
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- Forbes S., Davari M., Gnanasampanthan S. Persistence of antibody response to SARS-CoV-2 in a cohort of haemodialysis patients with COVID-19 [e-pub ahead of print]. Nephrol Dial Transplant. https://doi.org/10.1093/ndt/gfab066 Accessed April 15, 2021. - DOI - PMC - PubMed
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