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. 2021 May;10(10):3461-3473.
doi: 10.1002/cam4.3892. Epub 2021 May 1.

Chinese and global burdens of gastric cancer from 1990 to 2019

Yuxin He  1 , Yida Wang  2 , Fujuan Luan  1 , Zhuwen Yu  1 , Huang Feng  1 , Bingxin Chen  1 , Weichang Chen  1
Affiliations

Chinese and global burdens of gastric cancer from 1990 to 2019

Yuxin He et al. Cancer Med. 2021 May.

Abstract

Background: Gastric cancer is a common cancer in China. This project investigated the disease burden of gastric cancer from 1990 to 2019 in China and globally.

Methods: The global age-standardized rates (ASRs) were extracted from the Global Burden of Disease. Moreover, the estimated annual percentage changes (eAPCs) in the ASRs of incidence (ASIR), mortality (ASMR), and disability-adjusted life-years (DALYs) were calculated to determine the trends by countries and regions.

Results: In China, the ASIR declined from 37.56 to 30.64 per 100,000 and the ASMR declined from 37.73 to 21.72 per 100,000. The global ASIR decreased from 22.44 to 15.59 and the ASMR declined from 20.48 to 11.88 per 100,000 persons from 1990 to 2019. The ASIR was the lowest in Malawi (3.28 per 100,000) and the highest in Mongolia (43.7 per 100,000), whereas the ASMR was the lowest in the United States of America (3.40 per 100,000) and the highest in Mongolia (40.04 per 100,000) in 2019. The incidence of early-onset gastric cancer increased in China. The DALYs attributed to gastric cancer presented a slight decrease during the period. China had a higher mortality/incidence ratio (0.845) and 5-year prevalence (27.6/100,000) than most developed countries.

Conclusion: China presented a steady decline in the incidence and mortality rates for gastric cancer. The global ASIR, ASMR, and DALYs showed a slight rise decrease. Different patterns of gastric cancer rates and temporal trends have been identified in different geographical regions, indicating that specific strategies are needed to prevent the increase in some countries.

Keywords: China; disability-adjusted years; epidemiology; gastric cancer.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

FIGURE 1
FIGURE 1
World map of ASRs for gastric cancer in different countries and territories in 2019. (A) The ASIR of gastric cancer in 2019. (B) The ASMR of gastric cancer in 2019. (C) The age‐standardized DALYs of gastric cancer in 2019
FIGURE 2
FIGURE 2
The change trends of ASRs in gastric cancer by sex in China and globally from 1990 to 2019. (A) ASIR, China. (B) ASIR, world. (C) ASMR, China. (D) ASMR, world. (E) age‐standardized DALYs, China. (F) age‐standardized, world
FIGURE 3
FIGURE 3
Age‐specific rates of gastric cancer by sex in China and the world in 2019. (A) Incident rate, China. (B) Incident rate, world. (C) Mortality rate, China. (D) Mortality rate, world. (E) DALYs rate, China. (F) DALYs rate, world
FIGURE 4
FIGURE 4
Age‐specific trends in incidence rates of gastric cancer by age group from 1990 to 2019
See this image and copyright information in PMC

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