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Review
. 2021 Apr 13:2021:6697294.
doi: 10.1155/2021/6697294. eCollection 2021.

The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis

Yalewayker Tegegne  1 , Abebaw Worede  2 , Adane Derso  1 , Sintayehu Ambachew  2
Affiliations
Review

The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis

Yalewayker Tegegne et al. J Parasitol Res. .

Abstract

Background: Malaria is one of the most public health important and life-threatening parasitic infections caused by the protozoan parasite. Since children are immunologically naive to the malaria parasite, they are the main vulnerable groups. During malaria infection, they might have a complication of anemia, cerebral malaria, coma, respiratory distress, and a decrease in cognitive and behavioral improvement. Therefore, this review was aimed at determining the pooled prevalence of malaria among children in Ethiopia.

Methods: The current systematic review and meta-analysis were conducted based on the guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guideline. Electronic bibliographic databases such as Google Scholar, PubMed, and Science Direct were used for searching relevant literature. Besides, the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI) was used for critical appraisal of studies. Using the STATA 14 software, the pooled Meta logistic regression was computed to present the pooled prevalence with a 95% confidence interval (CI).

Result: The overall estimated pooled prevalence of malaria among children in Ethiopia was 9.07 (95% CI: 6.32, 11.82). Subgroup analysis based on malaria signs and symptoms showed that the pooled prevalence of malaria among asymptomatic and symptomatic children was 6.67% (95% CI: 0.36, 12.98) and 27.17% (95% CI: 18.59, 35.76), respectively.

Conclusion: The findings revealed a high prevalence of malaria among children in Ethiopia. As a result, still there is a need of improving and rechecking the existing malaria prevention and control measures of the country.

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Conflict of interest statement

All the authors announce that they have no any conflicts of interest.

Figures

Figure 1
Figure 1
The flow diagram refers to the selection of studies included for a systematic review and meta-analysis of the prevalence of malaria among children.
Figure 2
Figure 2
The pooled prevalence of malaria among children from random-effects model.
See this image and copyright information in PMC

References

    1. White N. Plasmodium Knowlesi: The Fifth Human Malaria Parasite. The University of Chicago Press; 2008. - PubMed
    1. WHO. World malaria report Brifing kit. WHO; 2019.
    1. FMoH F. National malaria guidelines. Malaria Diagnosis and Treatment. third. Vol. 2012. Addis Ababa, Ethiopia: Federal Minstery of Health Ethiopia; 2012.
    1. MoH F. D. E. National Malaria Guidelines. Third. Addis Ababa: Federal Minstery of Health Ethiopia;
    1. Jakubowski A., Stearns S. C., Kruk M. E., Angeles G., Thirumurthy H. The US President’s Malaria Initiative and under-5 child mortality in sub-Saharan Africa: a difference-in-differences analysis. PLoS Medicine. 2017;14(6, article e1002319) doi: 10.1371/journal.pmed.1002319. - DOI - PMC - PubMed

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