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Case Reports
. 2021 Apr 16:9:650697.
doi: 10.3389/fped.2021.650697. eCollection 2021.

Case Report: MIS-C Temporarily Associated With COVID-19 Complicated by Reye's Syndrome

Fabrício Silva Pessoa  1   2   3   4 , Eliza Maria da Costa Brito Lacerda  1 , Valdênia Costa Gonçalves  2   3 , Barbara Neiva Tanaka  2   3
Affiliations
Case Reports

Case Report: MIS-C Temporarily Associated With COVID-19 Complicated by Reye's Syndrome

Fabrício Silva Pessoa et al. Front Pediatr. .

Abstract

We describe a 7-year-old child with multisystemic inflammatory syndrome that was temporarily associated with the novel coronavirus disease which evolved into serious illness, with coronary aneurysm, using human immunoglobulin and acetylsalicylic acid, in which clinical manifestations including hepatitis, convulsions, and coma were aggravated with Reye's syndrome. To date, there has been no report of the association of multisystemic inflammatory syndrome that is temporarily associated with the novel coronavirus disease and Reye's syndrome.

Keywords: COVID-19; COVID-19 pandemic; Reye syndrome; SARS-CoV-2 (COVID-19); multisystem inflammatory syndrome in children.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(A) Presence of bilateral, nonexudative conjunctival hyperemia. (B) Maculopapular lesions in the palmoplantar region. (C) Presence of mucosal changes with peeling lip and raspberry tongue.
Figure 2
Figure 2
(A) Pretreatment echocardiographic images of the left main coronary artery measuring 3.762 mm (Z score +3.22). (B) Pretreatment echocardiographic images of the proximal right coronary measuring 3.38 mm (Z score +2.86). (C) Posttreatment echocardiographic images of the left main coronary artery measuring 3.28 mm (Z score +2.04). (D) Posttreatment echocardiographic images of the right proximal coronary artery measuring 2.87 mm (Z score +1.66).
See this image and copyright information in PMC

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