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Review
. 2021 Jun:34:102318.
doi: 10.1016/j.pdpdt.2021.102318. Epub 2021 Apr 30.

Application of photodynamic therapy in immune-related diseases

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Review

Application of photodynamic therapy in immune-related diseases

Dan Yang et al. Photodiagnosis Photodyn Ther. 2021 Jun.

Abstract

Photodynamic therapy (PDT) is a therapeutic modality that utilizes photodamage caused by photosensitizers and oxygen after exposure to a specific wavelength of light. Owing to its low toxicity, high selectivity, and minimally invasive properties, PDT has been widely applied to treat various malignant tumors, premalignant lesions, and infectious diseases. Moreover, there is growing evidence of its immunomodulatory effects and potential for the treatment of immune-related diseases. This review mainly focuses on the effect of PDT on immunity and its application in immune-related diseases.

Keywords: Immune-Related diseases; Immunomodulation; Photodynamic therapy.

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