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. 2022 Jun;16(3):419-431.
doi: 10.31616/asj.2020.0285. Epub 2021 May 6.

Physical Functions and Comorbidity Affecting Collapse at 4 or More Weeks after Admission in Patients with Osteoporotic Vertebral Fractures: A Prospective Cohort Study

Takuya Umehara  1   2 , Ayaka Inukai  2 , Daisuke Kuwahara  2 , Ryo Kaneyashiki  2 , Akinori Kaneguchi  1 , Miwako Tsunematsu  3 , Masayuki Kakehashi  3
Affiliations

Physical Functions and Comorbidity Affecting Collapse at 4 or More Weeks after Admission in Patients with Osteoporotic Vertebral Fractures: A Prospective Cohort Study

Takuya Umehara et al. Asian Spine J. 2022 Jun.

Abstract

Study design: A prospective cohort study.

Purpose: This study aimed to reveal physical functions and comorbidity affecting collapse at ≥4 weeks after hospital admission of patients with osteoporotic vertebral fracture.

Overview of literature: Only a few studies have investigated the influence of physical function and activity on collapse in patients with osteoporotic vertebral fractures.

Methods: This prospective cohort study analyzed patients with osteoporotic vertebral fractures admitted to the hospital between March 2018 and October 2019. Logistic regression analysis was performed to explore the predictors of vertebral collapse at >4 weeks after admission. Model 1 used basic medical information and physical functions at admission; model 2 used basic medical information and physical function and activity at >4 weeks after admission.

Results: In the model 1 results of logistic regression analysis, cardiovascular disease (odds ratio [OR], 12.27; 95% confidence interval [CI], 1.28-117.91) was extracted as a factor affecting vertebral collapse at ≥4 weeks after admission. In the model 2 results of logistic regression analysis, cardiovascular disease (OR, 34.57; 95% CI, 2.53-471.74), movement control during one leg standing at 4 weeks (OR, 7.25; 95% CI, 1.36-38.71), and Pain Catastrophizing Scale score at 4 weeks (OR, 1.11; 95% CI, 1.01-1.21) were extracted as factors affecting vertebral collapse at ≥4 weeks after admission.

Conclusions: Our results indicate that physical functions and comorbidity affect collapse at ≥4 weeks after admission in patients with osteoporotic vertebral fractures.

Keywords: Activity; Collapse; Osteoporotic vertebral fractures; Physical function.

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Conflict of interest statement

Conflict of interest

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
(A–D) Semiquantitative method severity classification.
Fig. 2
Fig. 2
Flow chart of osteoporotic vertebral fractures patients.
Fig. 3
Fig. 3
Model 1: cutoff value of score when the state variable by receiver operating characteristic curve is set to vertebral collapse at >4 weeks post admission. AUC, area under the curve.
Fig. 4
Fig. 4
Model 2: cutoff value of score when the state variable by receiver operating characteristic curve is set to vertebral collapse at >4 weeks post-admission. AUC, area under the curve.
See this image and copyright information in PMC

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