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Editorial
. 2021 May 18;10(10):e021675.
doi: 10.1161/JAHA.121.021675. Epub 2021 May 4.

Getting Sympathetic About Air Pollution Exposure

Affiliations
Editorial

Getting Sympathetic About Air Pollution Exposure

Robert D Brook et al. J Am Heart Assoc. .
No abstract available

Keywords: Editorials; air pollution; sympathetic nerve activity; sympathetic nervous system.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1. Potential pathways responsible for air pollution–induced autonomic imbalance and the health consequences.
AT‐2 indicates angiotensin‐2; BP, blood pressure; CHF, congestive heart failure; CNS, central nervous system; DEP, diesel exhaust pollution; ET‐1, endothelin‐1; HPAA, hypothalamic pituitary adrenal axis; HR, heart rate; MI, myocardial infarction; NE, norepinephrine; PM, particulate matter; PSNS, parasympathetic nervous system; SNS, sympathetic nervous system; TRP, transient receptor potential; and UFP, ultrafine particle.

Comment on

References

    1. Rajagopalan S, Al‐Kindi SG, Brook RD. Air pollution and cardiovascular disease: JACC state‐of‐the‐art review. J Am Coll Cardiol. 2018;72:2054–2070. DOI: 10.1016/j.jacc.2018.07.099. - DOI - PubMed
    1. Risk Factors Collaborators global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396:1223–1249. - PMC - PubMed
    1. HEI Panel on the Health Effects of Traffic‐Related Air Pollution. 2010. Traffic‐related air pollution: a critical review of the literature on emissions, exposure, and health effects. HEI Special Report 17. https://www.healtheffects.org/publication/traffic‐related‐air‐pollution‐.... Accessed March 24, 2021.
    1. Peters A, von Lot S, Heier M, Trentingalia I, Hormann A, Wichmann E, Lowel H. Exposure to traffic and the onset of myocardial infarction. N Engl J Med. 2004;351:1721–1730. DOI: 10.1056/NEJMoa040203. - DOI - PubMed
    1. Chen K, Schneider A, Cyrys J, Wolf K, Meisinger C, Heier M, von Scheidt W, Kuch B, Pitz M, Peters A, et al. Hourly exposure to ultrafine particle metrics and the onset of myocardial infarction in Augsburg, Germany. Environ Health Perspect. 2020;128:17003. DOI: 10.1289/EHP5478. - DOI - PMC - PubMed

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