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Review
. 2021:28:42.
doi: 10.1051/parasite/2021040. Epub 2021 May 3.

Piper aduncum essential oil: a promising insecticide, acaricide and antiparasitic. A review

Andrea Durofil  1 , Matteo Radice  2 , José Blanco-Salas  3 , Trinidad Ruiz-Téllez  3
Affiliations
Review

Piper aduncum essential oil: a promising insecticide, acaricide and antiparasitic. A review

Andrea Durofil et al. Parasite. 2021.

Abstract
in English, French

Several studies have assessed the potential of essential oils as substitutes for synthetic pesticides, in order to counter insect resistance to commercial pesticides. Piper aduncum L. is a very common shrub in the Amazon Rainforest and in other subtropical areas. The objective of this review was to analyse the existing information on P. aduncum essential oil as a raw material for new bioproducts for sustainable pest disease management. With this review, we collected and critically analysed 59 papers, representing all the studies that aimed to evaluate the essential oil properties of this species as an insecticide, acaricide and antiparasitic. The chemical composition differs depending on the origin, although phenylpropanoid dillapiole is the most cited component, followed by myristicin, 1,8-cineole and β-ocimene. Between the acaricidal, antiparasitic and synergistic activities, the insecticidal effects are highly promising, with optimal results against the malaria vector Aedes aegypti, with an LC50 that ranges between 57 and 200μg/mL. Acaricidal activity has mainly been reported against Tetranychus urticae, showing an LC50 that ranges between 5.83 and 7.17μg/mL. Antiparasitic activity has predominately been found on Leishmania amazonensis, and antipromastigote activity has been found to be between 23.8 and 25.9μg/mL. Concerning the synergistic effect between dillapiole and synthetic insecticides, four studies on Spodoptera frugiperda found promising results with cypermethrin. In this review, we highlighted the potential of P. aduncum essential oil as a biopesticide, also focusing on the lack of information about applied research. We also provide suggestions for future investigations.

Title: L’huile essentielle de Piper aduncum: un insecticide, acaricide et antiparasitaire prometteur. Une synthèse.

Abstract: Plusieurs études ont abordé le potentiel des huiles essentielles comme substitut aux pesticides de synthèse, afin de lutter contre la résistance des insectes aux pesticides commerciaux. Piper aduncum L. est un arbuste très commun dans la forêt amazonienne et dans d’autres zones subtropicales. L’objectif de ce travail est d’analyser les informations existantes sur l’huile essentielle de P. aduncum comme matière première de nouveaux bioproduits pour une gestion durable des maladies nuisibles. Dans cette synthèse, nous avons collecté et analysé de manière critique 59 articles, représentant toutes les études qui visaient à prouver les propriétés des huiles essentielles de cette espèce en tant qu’insecticide, acaricide et antiparasitaire. La composition chimique diffère selon la provenance, bien que le phénylpropanoïde dillapiole soit le composant le plus cité, suivi de la myristicine, du 1,8-cinéole et du β-ocimène. À côté des activités acaricide, antiparasitaire et de synergie avec les autres composants, les effets insecticides sont les plus prometteurs, avec des résultats optimaux contre le vecteur du paludisme Aedes aegypti, avec une CL50 comprise entre 57 et 200μg/mL. Une activité acaricide a été principalement rapportée contre Tetranychus urticae avec une CL50 comprise entre 5,83 et 7,17μg/mL. L’activité antiparasitaire a été montrée principalement sur Leishmania amazonensis et l’activité antipromastigote s’est avérée être comprise entre 23,8 et 25,9μg/mL. Concernant l’effet synergique entre le dillapiole et les insecticides synthétiques, quatre études sur Spodoptera frugiperda ont mis l’accent sur des résultats prometteurs avec la cyperméthrine. Avec cette étude, nous avons mis en évidence le potentiel de l’huile essentielle de P. aduncum en tant que biopesticide, en insistant sur le manque d’informations de la recherche appliquée et sur certaines propositions pour de futures recherches.

Keywords: Acaricide; Antiparasitic; Dillapiole; Essential oil; Insecticide; Piper aduncum.

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Figures

Figure 1
Figure 1
Piper aduncum L. (from Botanischen Wandplatet at http://www.plantillustrations.org/.
Figure 2
Figure 2
Biogeographic precedence of plant material in the reviewed papers.
Figure 3
Figure 3
Distribution of the focus of the topics in the revised bibliography.
See this image and copyright information in PMC

References

    1. Aciole EHP, Guimarães NN, Silva AS, Amorim EM, Nunomura SM, Garcia ACL, Cunha KS, Rohde C. 2014. Genetic toxicity of dillapiol and spinosad larvicides in somatic cells of Drosophila melanogaster. Pest Management Science, 70, 559–565. - PubMed
    1. Andrade PM De, Melo DC De, Alcoba AET, Ferreira Júnior WG, Pagotti MC, Magalhães LG, Santos TCL Dos, Crotti AEM, Alves CCF, Miranda MLD. 2018. Chemical composition and evaluation of antileishmanial and cytotoxic activities of the essential oil from leaves of Cryptocarya aschersoniana Mez. (Lauraceae Juss.). Anais da Academia Brasileira de Ciencias, 90, 2671–2678. - PubMed
    1. Araújo MJC, Câmara CAG, Born FS, Moraes MM, Badji CA. 2012. Acaricidal activity and repellency of essential oil from Piper aduncum and its components against Tetranychus urticae. Experimental and Applied Acarology, 57, 139–155. - PubMed
    1. de Araújo MJC, da Câmara CAG, de Souza Born F., Moraes MM de. 2020. Acaricidal activity of binary blends of essential oils and selected constituents against Tetranychus urticae in laboratory/greenhouse experiments and the impact on Neoseiulus californicus. Experimental and Applied Acarology, 80, 423–444. - PubMed
    1. Belzile AS, Majerus SL, Podeszfinski C, Guillet G, Durst T, Arnason JT. 2000. Dillapiol derivatives as synergists: Structure-activity relationship analysis. Pesticide Biochemistry and Physiology, 66, 33–40.

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