Optimism with Caution: Elexacaftor-Tezacaftor-Ivacaftor in Patients with Advanced Pulmonary Disease
- PMID: 33951409
- PMCID: PMC8513598
- DOI: 10.1164/rccm.202103-0682LE
Optimism with Caution: Elexacaftor-Tezacaftor-Ivacaftor in Patients with Advanced Pulmonary Disease
Comment in
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Reply to Kuek et al.: Optimism with Caution: Elexacaftor-Tezacaftor-Ivacaftor in Patients with Advanced Pulmonary Disease.Am J Respir Crit Care Med. 2021 Aug 1;204(3):372-374. doi: 10.1164/rccm.202103-0796LE. Am J Respir Crit Care Med. 2021. PMID: 33951399 Free PMC article. No abstract available.
Comment on
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Rapid Improvement after Starting Elexacaftor-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and Advanced Pulmonary Disease.Am J Respir Crit Care Med. 2021 Jul 1;204(1):64-73. doi: 10.1164/rccm.202011-4153OC. Am J Respir Crit Care Med. 2021. PMID: 33600738
References
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- Burgel P-R, Durieu I, Chiron R, Ramel S, Danner-Boucher I, Prevotat A, et al. French Cystic Fibrosis Reference Network Study Group. Rapid improvement after starting elexacaftor–tezacaftor–ivacaftor in patients with cystic fibrosis and advanced pulmonary disease. Am J Respir Crit Care Med. 2021;204 - PubMed
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- Heijerman HGM, McKone EF, Downey DG, Van Braeckel E, Rowe SM, Tullis E, et al. VX17-445-103 Trial Group. Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial. Lancet. 2019;394:1940–1948. - PMC - PubMed
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- Griese M, Costa S, Linnemann RW, Mall MA, McKone EF, Polineni D, et al. Safety and efficacy of elexacaftor/tezacaftor/ivacaftor for 24 weeks or longer in people with cystic fibrosis and 1 or more F508del alleles: Interim results of an open-label phase 3 clinical trial. Am J Respir Crit Care Med. 2021;203:381–385. - PMC - PubMed
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