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Comment
. 2021 May 4;33(5):847-848.
doi: 10.1016/j.cmet.2021.04.008.

Too much of a good thing: Excess exercise can harm mitochondria

Mark W Pataky  1 , K Sreekumaran Nair  2
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Comment

Too much of a good thing: Excess exercise can harm mitochondria

Mark W Pataky et al. Cell Metab. .
Free article

Abstract

Health benefits of aerobic exercise are indisputable and are closely related to the maintenance of mitochondrial energy homeostasis and insulin sensitivity. Flockhart et al. (2021) demonstrate, however, that a high volume of high-intensity aerobic exercise adversely affects mitochondrial function and may cause impaired glucose tolerance.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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