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Review
. 2021 May 5;18(1):28.
doi: 10.1186/s12981-021-00335-1.

COVID-19 and HIV infection co-pandemics and their impact: a review of the literature

Sivaporn Gatechompol  1   2 , Anchalee Avihingsanon  1   2 , Opass Putcharoen  3 , Kiat Ruxrungtham  4 , Daniel R Kuritzkes  5
Affiliations
Review

COVID-19 and HIV infection co-pandemics and their impact: a review of the literature

Sivaporn Gatechompol et al. AIDS Res Ther. .

Abstract

Coronavirus disease 2019 (COVID-19) was first detected in December 2019. In March 2020, the World Health Organization declared COVID-19 a pandemic. People with underlying medical conditions may be at greater risk of infection and experience complications from COVID-19. COVID-19 has the potential to affect People living with HIV (PLWH) in various ways, including be increased risk of COVID-19 acquisition and interruptions of HIV treatment and care. The purpose of this review article is to evaluate the impact of COVID-19 among PLWH. The contents focus on 4 topics: (1) the pathophysiology and host immune response of people infected with both SARS-CoV-2 and HIV, (2) present the clinical manifestations and treatment outcomes of persons with co-infection, (3) assess the impact of antiretroviral HIV drugs among PLWH infected with COVID-19 and (4) evaluate the impact of the COVID-19 pandemic on HIV services.

Keywords: COVID-19; Clinical; Co-infection; HIV; Outcome; Pathophysiology.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Pathophysiology and clinical manifestations of COVID-19. Created with BioRender.com
Fig. 2
Fig. 2
Host immune response following exposure to HIV. Created with BioRender.com
See this image and copyright information in PMC

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