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. 2021 Jul;32(7):1909-1917.
doi: 10.1111/jce.15074. Epub 2021 May 22.

The utility of a novel mapping algorithm utilizing vectors and global pattern of propagation for scar-related atrial tachycardias

Shunsuke Kuroda  1 , Oussama M Wazni  1 , Walid I Saliba  1 , Henry Hilow  1 , Bryan Baranowski  1 , Khaldoun G Tarakji  1 , Koji Higuchi  1 , Patrick Tchou  1 , Thomas Dresing  1 , John O Lopez  1 , Mandeep Bhargava  1 , Daniel J Cantillon  1 , Thomas Callahan  1 , John Rickard  1 , Hiroshi Nakagawa  1 , Elad Anter  1 , Ayman A Hussein  1
Affiliations

The utility of a novel mapping algorithm utilizing vectors and global pattern of propagation for scar-related atrial tachycardias

Shunsuke Kuroda et al. J Cardiovasc Electrophysiol. 2021 Jul.

Abstract

Background: Activation maps of scar-related atrial tachycardias (AT) can be challenging to interpret due to difficulty in inaccurate annotation of electrograms, and an arbitrarily predefined mapping window. A novel mapping software integrating vector data and applying an algorithmic solution taking into consideration global activation pattern has been recently described (Coherent™, Biosense Webster "Investigational").

Objective: We aimed to assess the investigational algorithm to determine the mechanism of AT compared with the standard algorithm.

Methods: This study included patients who underwent ablation of scar-related AT using the Carto 3 and the standard activation algorithm. The mapping data were analyzed retrospectively using the investigational algorithm, and the mechanisms were evaluated by two independent electrophysiologists.

Results: A total of 77 scar-related AT activation maps were analyzed (89.6% left atrium, median tachycardia cycle length of 273 ms). Of those, 67 cases with a confirmed mechanism of arrhythmia were used to compare the activation software. The actual mechanism of the arrhythmia was more likely to be identified with the investigational algorithm (67.2% vs. 44.8%, p = .009). In five patients with dual-loop circuits, 3/5 (60%) were correctly identified by the investigational algorithm compared to 0/5 (0%) with the standard software. The reduced atrial voltage was prone to lead to less capable identification of mechanism (p for trend: .05). The investigational algorithm showed higher inter-reviewer agreement (Cohen's kappa .62 vs. .47).

Conclusions: In patients with scar-related ATs, activation mapping algorithms integrating vector data and "best-fit" propagation solution may help in identifying the mechanism and the successful site of termination.

Keywords: activation mapping; algorithm; catheter ablation; mechanisms of arrhythmias; scar-related atrial tachycardia.

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References

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