Patterns of cost-related medication underuse among Canadian adults with cancer: a cross-sectional study using survey data
- PMID: 33958383
- PMCID: PMC8157980
- DOI: 10.9778/cmajo.20200186
Patterns of cost-related medication underuse among Canadian adults with cancer: a cross-sectional study using survey data
Abstract
Background: Cost-related medication underuse (CRMU) has been reported within the general population in Canada. In this study, we assessed patterns of CRMU among Canadian adults with cancer.
Methods: This is a cross-sectional study using survey data. We accessed data sets from the 2015/16 Canadian Community Health Survey (CCHS) and reviewed the records of adults (≥ 18 yr) with a history of cancer who were prescribed medication in the previous 12 months. We collected information about sociodemographic features, health behaviours and CRMU, and conducted a multivariable logistic regression analysis for factors associated with CRMU.
Results: A total of 8581 participants were eligible for the current study. In the weighted multivariable logistic regression analysis, the following factors were associated with CRMU: younger age (odds ratio [OR] 2.55, 95% confidence interval [CI] 1.79-3.63), female sex (male sex v. female sex OR 0.62, 95% CI 0.44-0.88), Indigenous racial background (Indigenous v. White OR 2.37, 95% CI 1.49- 3.77), unmarried status (OR 1.59, 95% CI 1.09-2.30), poor self-perceived health (excellent v. poor self-perceived health OR 0.36, 95% CI 0.17-0.77), lower annual income (< $20 000 v. income ≥ $80 000 OR 3.08, 95% CI 1.75-5.41) and lack of insurance for prescription medications (OR 2.49, 95% CI 1.77-3.50).
Interpretation: The toll of CRMU among adults seems to be unequally carried by women, racial minorities, and younger (< 65 yr) and uninsured patients with cancer. Discussion about a national pharmacare program for people without private insurance is needed.
© 2021 CMA Joule Inc. or its licensors.
Conflict of interest statement
Competing interests: Omar Abdel-Rahman declares having recently participated on an advisory board for Eisai Canada for a topic unrelated to the manuscript. No other competing interests were declared.
Figures
Similar articles
-
Cost-related prescription nonadherence in the United States and Canada: a system-level comparison using the 2007 International Health Policy Survey in Seven Countries.Clin Ther. 2009 Jan;31(1):213-9. doi: 10.1016/j.clinthera.2009.01.006. Clin Ther. 2009. PMID: 19243719
-
National Trends in Cessation Counseling, Prescription Medication Use, and Associated Costs Among US Adult Cigarette Smokers.JAMA Netw Open. 2019 May 3;2(5):e194585. doi: 10.1001/jamanetworkopen.2019.4585. JAMA Netw Open. 2019. PMID: 31125108 Free PMC article.
-
Cost-related medication nonadherence among over-indebted individuals enrolled in statutory health insurance in Germany: a cross-sectional population study.BMC Health Serv Res. 2019 Nov 26;19(1):887. doi: 10.1186/s12913-019-4710-0. BMC Health Serv Res. 2019. PMID: 31771583 Free PMC article.
-
Impact of the Patient Protection and Affordable Care Act on cost-related medication underuse in nonelderly adult cancer survivors.Cancer. 2020 Jun 15;126(12):2892-2899. doi: 10.1002/cncr.32836. Epub 2020 Mar 18. Cancer. 2020. PMID: 32187662
-
The effect of cost on adherence to prescription medications in Canada.CMAJ. 2012 Feb 21;184(3):297-302. doi: 10.1503/cmaj.111270. Epub 2012 Jan 16. CMAJ. 2012. PMID: 22249979 Free PMC article.
Cited by
-
Not All Canadian Cancer Patients Are Equal-Disparities in Public Cancer Drug Funding across Canada.Curr Oncol. 2022 Mar 17;29(3):2064-2072. doi: 10.3390/curroncol29030166. Curr Oncol. 2022. PMID: 35323366 Free PMC article. Review.
-
Association between under-dose of enzyme replacement therapy and quality of life in adults with late-onset Pompe disease in China: A retrospective matched cohort study.PLoS One. 2024 Sep 17;19(9):e0310534. doi: 10.1371/journal.pone.0310534. eCollection 2024. PLoS One. 2024. PMID: 39288112 Free PMC article.
-
Exploring Biologic Treatment Hesitancy Among Black and Indigenous Populations in Canada: a Review.J Racial Ethn Health Disparities. 2023 Apr;10(2):942-951. doi: 10.1007/s40615-022-01282-x. Epub 2022 Apr 27. J Racial Ethn Health Disparities. 2023. PMID: 35476223 Free PMC article. Review.
References
-
- Canada’s health care system. Ottawa: Health Canada; [accessed 2020 Aug. 2]. modified 2019 Sept 17. Available: www.canada.ca/en/health-canada/services/health-care-system/reports-publi....
-
- Canada Health Act (R.S.C., 1985c. C-6) [accessed 2020 Aug. 2]. Available: https://laws-lois.justice.gc.ca/eng/acts/C-6/
-
- Understand how health care works in Canada. Ottawa: Immigration, Refugees and Citizenship Canada; [accessed 2020 Aug. 2]. modified 2020 Oct. 28. Available: www.canada.ca/en/immigration-refugees-citizenship/services/new-immigrant....
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical