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Case Reports
. 2021 Mar 2;12(2):312-315.
doi: 10.4103/idoj.IDOJ_568_20. eCollection 2021 Mar-Apr.

The Puzzle of Papules Over Face and Extrafacial Areas: A Rare Case of Disseminated Idiopathic T-Cell Pseudolymphoma

Sumit A Hajare  1 , Vaishali H Wankhade  2 , Gitesh U Sawatkar  3 , Rajesh Pratap Singh  2
Affiliations
Case Reports

The Puzzle of Papules Over Face and Extrafacial Areas: A Rare Case of Disseminated Idiopathic T-Cell Pseudolymphoma

Sumit A Hajare et al. Indian Dermatol Online J. .

Abstract

Papular lesions over face have a wide range of differential diagnoses. The clinical differentiation among these is difficult and often requires clinicopathological correlation. We hereby report the case of a 28 year old female presenting with numerous skin colored papular lesions over face, pinna and upper limbs.

Keywords: Cutaneous lymphoid hyperplasia; lichenoid pseudovesicular papular eruption on nose; lymphocytic infiltrate; lymphocytoma cutis; papules over nose.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Multiple skin colored to erythematous, translucent, firm papules were present bilaterally symmetrical over nose, cheeks, and forehead
Figure 2
Figure 2
(a and b) Clinical image showing skin-colored papules present bilaterally over pinna, pre- and post-auricular areas. (c and d) Multiple erythematous and lichenoid papules over both forearms and dorsum of hands
Figure 3
Figure 3
Histopathological image showing (a) Normal epidermis with clear subepidermal zone, and dense and diffuse lymphocytic infiltrate throughout the dermis (H and E, ×20). (b) Similar findings seen on higher magnification (×40)
Figure 4
Figure 4
Immunohistochemistry staining for (a) CD3+ T cells, (b) CD4+ T cells, (c) CD5+ T cells, (d) CD8+ T cells showing infiltrate strongly positive for CD3+ and CD8+ T cells
Figure 5
Figure 5
Immunohistochemistry staining for (a) bcl-2, (b) CD20+ B cells, (c) CD68+ histiocytes, (d) Ki-67 showing infiltrate weakly positive for CD20+ B cells and CD68+ histiocytes
Figure 6
Figure 6
Post treatment clinical image of face showing good response to treatment except few lesions over nose
Figure 7
Figure 7
Post treatment clinical images of (a and b) bilateral pinna, pre- and post-auricular areas, and (c and d) both upper limbs showing resolution of lesions
See this image and copyright information in PMC

References

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