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. 2021 May;26(18):2100423.
doi: 10.2807/1560-7917.ES.2021.26.18.2100423.

Case series of four re-infections with a SARS-CoV-2 B.1.351 variant, Luxembourg, February 2021

Thérèse Staub  1 , Vic Arendt  1 , Esther Calvo Lasso de la Vega  1 , Pierre Braquet  1 , Christian Michaux  1 , Michel Kohnen  2 , Chantal Tsobo  2 , Tamir Abdelrahman  3 , Anke Wienecke-Baldacchino  3 , Jean-Hugues Francois  2
Affiliations

Case series of four re-infections with a SARS-CoV-2 B.1.351 variant, Luxembourg, February 2021

Thérèse Staub et al. Euro Surveill. 2021 May.

Abstract

We describe four SARS-CoV-2 re-infections with a B.1.351 variant in 2021, in healthcare workers (HCWs) previously infected in 2020, before detection of this variant in Europe. Cases live in France, near the border with Luxembourg, where variants B.1.351 and B.1.1.7 circulated. All work in the same hospital unit where a cluster of COVID 19 with B1.351 variant occurred, affecting patients and HCWs. Before the cluster onset, HCWs used surgical masks, as per recommendations. After cluster onset, HCWs used FFP2 masks.

Keywords: COVID-19; PCR; SARS-CoV-2; healthcare workers; outbreak; re-infection; variant.

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Conflict of interest statement

Conflict of interest: None declared.

References

    1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China,2019. N Engl J Med. 2020;382(8):727-33. 10.1056/NEJMoa2001017 - DOI - PMC - PubMed
    1. Cohen JI, Burbelo PD. Reinfections with SARS-CoV-2: Implications for vaccines. Clin Inf Dis. 2020;ciaa1866. 10.1093/cid/ciaa1866 PMID:33338197 - DOI - PMC - PubMed
    1. Kellam P, Barclay W. The dynamics of humoral immune responses following SARS-CoV-2 infection and the potential for reinfection. J Gen Virol. 2020;101(8):791-7. 10.1099/jgv.0.001439 - DOI - PMC - PubMed
    1. To KK, Hung IF, Ip JD, Chu AW, Chan WM, Tam AR, et al. COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing. Clin Infect Dis. 2020;ciaa1275. - PMC - PubMed
    1. Larson D, Brodniak SL, Voegtly LJ, Cer RZ, Glang LA, Malagon FJ, et al. A case of early re-infection with SARS-CoV-2. Clin Infect Dis. 2020;ciaa1436. - PMC - PubMed

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