Glimpses into evolutionary trajectories of SARS-CoV-2: emerging variants and potential immune evasion routes
- PMID: 33960807
- PMCID: PMC8111931
- DOI: 10.2217/fmb-2020-0300
Glimpses into evolutionary trajectories of SARS-CoV-2: emerging variants and potential immune evasion routes
Abstract
Tweetable abstract An opinion on the coronaviruses' evolution paradoxes, the continuing adaptation of the SARS-CoV-2 in humans following the zoonotic transmission, and clues into escape routes from host immune responses.
Keywords: APOBEC; COVID-19; SARS-CoV-2 variants of concern; adaptation; coronavirus; genetic diversity; genome evolution; immune escape; spike; vaccines.
Similar articles
-
Impact of vaccination on SARS-CoV-2 evolution and immune escape variants.Vaccine. 2024 Aug 30;42(21):126153. doi: 10.1016/j.vaccine.2024.07.054. Epub 2024 Jul 26. Vaccine. 2024. PMID: 39060204
-
Implication of SARS-CoV-2 Immune Escape Spike Variants on Secondary and Vaccine Breakthrough Infections.Front Immunol. 2021 Nov 3;12:742167. doi: 10.3389/fimmu.2021.742167. eCollection 2021. Front Immunol. 2021. PMID: 34804022 Free PMC article. Review.
-
Atypical Divergence of SARS-CoV-2 Orf8 from Orf7a within the Coronavirus Lineage Suggests Potential Stealthy Viral Strategies in Immune Evasion.mBio. 2021 Jan 19;12(1):e03014-20. doi: 10.1128/mBio.03014-20. mBio. 2021. PMID: 33468697 Free PMC article.
-
Omicron: What Makes the Latest SARS-CoV-2 Variant of Concern So Concerning?J Virol. 2022 Mar 23;96(6):e0207721. doi: 10.1128/jvi.02077-21. Epub 2022 Mar 23. J Virol. 2022. PMID: 35225672 Free PMC article. Review.
-
Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants.Nat Commun. 2021 Nov 4;12(1):6405. doi: 10.1038/s41467-021-26602-3. Nat Commun. 2021. PMID: 34737266 Free PMC article.
Cited by
-
Paired associated SARS-CoV-2 spike variable positions: a network analysis approach to emerging variants.mSystems. 2023 Aug 31;8(4):e0044023. doi: 10.1128/msystems.00440-23. Epub 2023 Jul 11. mSystems. 2023. PMID: 37432011 Free PMC article.
-
Incidence, Risk, and Severity of SARS-CoV-2 Reinfections in Children and Adolescents Between March 2020 and July 2022 in Serbia.JAMA Netw Open. 2023 Feb 1;6(2):e2255779. doi: 10.1001/jamanetworkopen.2022.55779. JAMA Netw Open. 2023. PMID: 36780157 Free PMC article.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous