The future belongs to those who prepare for it today
- PMID: 33961757
- DOI: 10.1016/j.stem.2021.04.014
The future belongs to those who prepare for it today
Abstract
Hippocampal neural stem cells (NSCs) and neurogenesis decline sharply with age, though a small population remains. Two articles in this issue of Cell Stem Cell by Ibrayeva et al. (2021) and Harris et al. (2021) indicate the presence of subpopulations of NSCs whose dynamics of activation and self-renewal change over time and may be key to NSC preservation.
Copyright © 2021 Elsevier Inc. All rights reserved.
Comment on
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Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population.Cell Stem Cell. 2021 May 6;28(5):863-876.e6. doi: 10.1016/j.stem.2021.01.003. Epub 2021 Feb 12. Cell Stem Cell. 2021. PMID: 33581058 Free PMC article.
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Early stem cell aging in the mature brain.Cell Stem Cell. 2021 May 6;28(5):955-966.e7. doi: 10.1016/j.stem.2021.03.018. Epub 2021 Apr 12. Cell Stem Cell. 2021. PMID: 33848469 Free PMC article.
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