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Comment
. 2021 May 6;28(5):787-789.
doi: 10.1016/j.stem.2021.04.025.

Human-monkey chimeras: Monkey see, monkey do

Victoria L Mascetti  1 , Roger A Pedersen  2
Affiliations
Free article
Comment

Human-monkey chimeras: Monkey see, monkey do

Victoria L Mascetti et al. Cell Stem Cell. .
Free article

Abstract

Recently in Cell, Tan et al. (2021) report the successful generation of human-monkey chimeras in vitro, providing an opportunity for new insights into the biology of human stem cells and early human development in an embryonic environment that is evolutionary closer to human than previously studied rodent and domestic species.

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Conflict of interest statement

Declaration of interests R.A.P. is an advisor and holds stock options in BIT BIO.

Comment on

  • Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo.
    Tan T, Wu J, Si C, Dai S, Zhang Y, Sun N, Zhang E, Shao H, Si W, Yang P, Wang H, Chen Z, Zhu R, Kang Y, Hernandez-Benitez R, Martinez Martinez L, Nuñez Delicado E, Berggren WT, Schwarz M, Ai Z, Li T, Rodriguez Esteban C, Ji W, Niu Y, Izpisua Belmonte JC. Tan T, et al. Cell. 2021 Apr 15;184(8):2020-2032.e14. doi: 10.1016/j.cell.2021.03.020. Cell. 2021. PMID: 33861963

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