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Review
. 2021 Jul:206:173195.
doi: 10.1016/j.pbb.2021.173195. Epub 2021 May 5.

Effect of child abuse and neglect on schizophrenia and other psychotic disorders

Affiliations
Review

Effect of child abuse and neglect on schizophrenia and other psychotic disorders

Barbara H Chaiyachati et al. Pharmacol Biochem Behav. 2021 Jul.

Abstract

Childhood experiences impact long-term physical and behavioral health outcomes including potential risk for schizophrenia and psychosis. Negative experiences, such as child abuse and neglect, have been specifically associated with risk for schizophrenia and psychosis. This review provides a brief overview of child abuse and neglect, including its position within the larger field of trauma and adversity and its long term consequences. The link to schizophrenia is then explored. Principles of treatment and outcomes for schizophrenia with antecedent child abuse and neglect are then reviewed. Finally, next steps and points of prevention are highlighted.

Keywords: Adverse childhood experiences; Child abuse; Child maltreatment; Child neglect; Psychosis; Schizophrenia.

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Figures

Figure 1:
Figure 1:
Schematic presentation of the pathway to psychosis. CHR: Clinical high risk.

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References

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