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Multicenter Study
. 2021 Oct:71:102378.
doi: 10.1016/j.anaerobe.2021.102378. Epub 2021 May 7.

Three is a crowd: Clinical outcomes of a twice daily versus a thrice daily metronidazole dosing strategy from a multicenter study

Sunish Shah  1 , Kathleen Adams  2 , Jacob Merwede  3 , Dayna McManus  4 , Jeffrey Topal  5
Affiliations
Multicenter Study

Three is a crowd: Clinical outcomes of a twice daily versus a thrice daily metronidazole dosing strategy from a multicenter study

Sunish Shah et al. Anaerobe. 2021 Oct.

Abstract

This was a multicenter, retrospective study of patients with anaerobic bacteremia comparing metronidazole 500 mg every 8 h versus 500 mg every 12 h. Of 782 patients reviewed, 85 met inclusion criteria. There was no significant difference in mortality, length of stay, or escalation of therapy between dosing strategies.

Keywords: 12 hour; Anaerobic bacteremia; Dose; Metronidazole.

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Conflict of interest statement

Declaration of competing interest All authors report no conflicts of interest.

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