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Case Reports
. 2021 Jan-Dec:9:23247096211012224.
doi: 10.1177/23247096211012224.

Recurrent Colon Cancer: Presentation With Disseminated Intravascular Coagulation From Disseminated Carcinomatosis of the Bone Marrow

Sai Prasad Desikan  1 , Nathan Mclaughlin  1 , Charles McClain  1 , Raman Desikan  1
Affiliations
Case Reports

Recurrent Colon Cancer: Presentation With Disseminated Intravascular Coagulation From Disseminated Carcinomatosis of the Bone Marrow

Sai Prasad Desikan et al. J Investig Med High Impact Case Rep. 2021 Jan-Dec.

Abstract

Diffuse carcinomatosis of the bone marrow (DCBM) is a rare clinical condition characterized by diffuse bone marrow involvement with hematological changes. This case study concerns a patient who presented with DCBM secondary to colon cancer with diffuse intravascular coagulation. This is a rare presentation of DCBM in colon cancer. The case study also elaborates on clinical features, pathogenesis, and therapy of this unique presentation.

Keywords: colorectal cancer; diffuse carcinomatosis of the bone marrow; disseminated intravascular coagulation.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Poorly differentiated mucinous adenocarcinoma (black arrows) invading through the muscularis propria.
Figure 2.
Figure 2.
Cytokeratin staining of the bone marrow, positive for CK20 as well as CDX2 and negative for CK7 suggesting metastatic carcinoma.
See this image and copyright information in PMC

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