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Review
. 2021 Apr;37(Suppl 2):254-260.
doi: 10.1007/s12055-020-01071-3. Epub 2020 Nov 23.

Review of acute kidney injury and continuous renal replacement therapy in pediatric extracorporeal membrane oxygenation

Christopher Jenks  1 , Lakshmi Raman  2   3 , Archana Dhar  2   3
Affiliations
Review

Review of acute kidney injury and continuous renal replacement therapy in pediatric extracorporeal membrane oxygenation

Christopher Jenks et al. Indian J Thorac Cardiovasc Surg. 2021 Apr.

Abstract

Purpose: To review the relevant literature of acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) as it relates to pediatric extracorporeal membrane oxygenation (ECMO).

Methods: Available online relevant literature.

Results: ECMO is a therapeutic modality utilized to support patients with refractory respiratory and/or cardiac failure. AKI and fluid overload (FO) are frequently observed in this patient population. There are multiple modalities that can be utilized for AKI and FO which include the following: diuretics, in-line hemofiltration, and CRRT. There are multiple considerations when using CRRT with ECMO including access, CRRT flows, hemolysis, anticoagulation, and CRRT termination.

Conclusion: While each ECMO center has its own set of equipment, experiences, and practices, it is imperative that the international ECMO community continues to work together to provide an evidence-based approach to address the morbidity and mortality associated with AKI and FO.

Keywords: AKI; CRRT; ECLS; ECMO; Fluid overload.

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Conflict of interest statement

Conflict of interestThe authors declare that they have no conflict of interest.

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