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Case Reports
. 2020 Sep-Dec;24(3):590.
doi: 10.4103/jomfp.JOMFP_186_20. Epub 2021 Jan 9.

Sclerosing polycystic adenosis of minor salivary glands: Report of a rare case with diagnostic approach and review of literature

Surya Narayan Das  1 , Kirti Jyoti  1 , Rachna Rath  1 , Bodhiswata Pattnaik  1
Affiliations
Case Reports

Sclerosing polycystic adenosis of minor salivary glands: Report of a rare case with diagnostic approach and review of literature

Surya Narayan Das et al. J Oral Maxillofac Pathol. 2020 Sep-Dec.

Abstract

Sclerosing polycystic adenosis (SPA) is an uncommon entity occurring in the salivary glands, with majority of the cases reported in major salivary glands reminiscent of fibrocystic disease of the breast. SPA arising in minor salivary glands of the oral cavity constitutes an exceedingly rare phenomenon. Here, we report a case of SPA that presented as a solitary, submucosal mass on the left lower labial mucosa in a 19-year-old male. The pathology features and a clinicopathologic diagnostic approach highlighting key features are discussed here. Similar cases published in the English literature are reviewed.

Keywords: Mouth; salivary glands; sclerosing polycystic adenosis.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) A well-defined solitary, round, soft-to-firm submucosal swelling on the left lower labial mucosa. (b) Gross specimen was smooth surfaced, was grayish white and was firm
Figure 2
Figure 2
Histopathological image showing (a) lobular arrangement of variably sized microcysts in a densely sclerotic background (×40, H and E). (b) Cystically dilated ductal structures with mild chronic inflammatory infiltrate (×100, H and E), (c) dilated ducts lined by flattened-to-cuboidal cells with eosinophilic cytoplasm and few areas showing ductal hyperplasia (×400, H and E), (d and e) apocrine-like and mucinous metaplasia of duct (×400 H and E), (f) calponin stain demonstrating prominent peripheral staining of myoepithelial cell layer (×100, immunohistochemistry)
Figure 3
Figure 3
Clinicopathological diagnostic approach for sclerosing polycystic adenosis
See this image and copyright information in PMC

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