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Review
. 2021 Apr 21:12:607157.
doi: 10.3389/fpls.2021.607157. eCollection 2021.

Extraribosomal Functions of Cytosolic Ribosomal Proteins in Plants

Wei Xiong  1   2 , Ting Lan  1   2 , Beixin Mo  1
Affiliations
Review

Extraribosomal Functions of Cytosolic Ribosomal Proteins in Plants

Wei Xiong et al. Front Plant Sci. .

Abstract

Ribosomes are basic translational machines in all living cells. The plant cytosolic ribosome is composed of four rRNAs and approximately 81 ribosomal proteins (RPs). In addition to the fundamental functions of RPs in the messenger RNA decoding process as well as in polypeptide synthesis and ribosome assembly, extraribosomal functions of RPs that occur in the absence of the ribosome have been proposed and studied with respect to RPs' ability to interact with RNAs and non-ribosomal proteins. In a few cases, extraribosomal functions of several RPs have been demonstrated with solid evidences in plants, including microRNA biogenesis, anti-virus defenses, and plant immunity, which have fascinated biologists. We believe that the widespread duplication of RP genes in plants may increase the potential of extraribosomal functions of RPs and more extraribosomal functions of plant RPs will be discovered in the future. In this article we review the current knowledge concerning the extraribosomal functions of RPs in plants and described the prospects for future research in this fascinating area.

Keywords: RP genes; extraribosomal functions; gene duplication; plant ribosomal protein; ribosome.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Extraribosomal functions of RPL24B in Arabidopsis. RPL24B was translated by cytosolic ribsomes and a portion of RPL24B was translocated from the cytoplasm into the nucleus. In nucleus, RPL24B indirectly influences MIR transcription and directly binds primary miRNAs promoting their processing (Li et al., 2017).
FIGURE 2
FIGURE 2
Potential extraribosomal functions of cytosolic RPs in plants and relevant methods and appraoches to analyze extraribosomal function of RPs.
See this image and copyright information in PMC

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References

    1. Abdulkina L. R., Kobayashi C., Lovell J. T., Chastukhina I. B., Aklilu B. B., Agabekian I. A., et al. (2019). Components of the ribosome biogenesis pathway underlie establishment of telomere length set point in Arabidopsis. Nat. Commun. 10:5479. - PMC - PubMed
    1. Alix K., Gerard P. R., Schwarzacher T., Heslop-Harrison J. S. P. (2017). Polyploidy and interspecific hybridization: partners for adaptation, speciation and evolution in plants. Ann. Bot. 120 183–194.10.1093/aob/mcx079 - DOI - PMC - PubMed
    1. Ban N., Nissen P., Hansen J., Moore P. B., Steitz T. A. (2000). The complete atomic structure of the large ribosomal subunit at 2.4 Å resolution. Science 289 905–920. 10.1126/science.289.5481.905 - DOI - PubMed
    1. Barakat A., Szickmiranda K., Chang I., Guyot R., Blanc G., Cooke R., et al. (2001). The organization of cytoplasmic ribosomal protein genes in the Arabidopsis genome. Plant Physiol. 127 398–415.10.1104/pp.127.2.398 - DOI - PMC - PubMed
    1. Blumenthal T., Carmichael G. G. (1979). RNA replication: function and structure of Qbeta-replicase. Annu. Rev. Biochem. 48 525–548. 10.1146/annurev.bi.48.070179.002521 - DOI - PubMed

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