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Case Reports
. 2021:24:e01143.
doi: 10.1016/j.idcr.2021.e01143. Epub 2021 Apr 30.

Guillain-Barré syndrome following the first dose of SARS-CoV-2 vaccine: A temporal occurrence, not a causal association

Osakpolor Ogbebor  1 , Harshit Seth  2 , Zaw Min  1 , Nitin Bhanot  1
Affiliations
Case Reports

Guillain-Barré syndrome following the first dose of SARS-CoV-2 vaccine: A temporal occurrence, not a causal association

Osakpolor Ogbebor et al. IDCases. 2021.

Abstract

Safety monitoring is of paramount importance for vaccines authorized for emergent use (EUA) by the US Food and Drug Administration (FDA) against SARS-CoV-2. Mass immunization is an essential tool to end the current pandemic, but vaccine surveillance is necessary to identify any potentially associated harms. At the same time, probability of temporal bias should be borne in mind before making conclusions about causality between the vaccine and an attributable undesired effect. We report a case of Guillain-Barré syndrome after the first dose of SARS-CoV-2 vaccine and believe this is a temporal, rather than causal association.

Keywords: Guillain-Barré syndrome; SARS-CoV-2 vaccine.

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Conflict of interest statement

The authors report no declarations of interest.

References

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