Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Oct;180(10):3129-3139.
doi: 10.1007/s00431-021-04092-1. Epub 2021 May 10.

Aortic valve surgery: management and outcomes in the paediatric population

Mariam Zaidi  1 , Ganeshkumar Premkumar  2 , Rimel Naqvi  2 , Arwa Khashkhusha  3 , Zahra Aslam  3 , Adil Ali  4 , Abdulla Tarmahomed  5 , Amr Ashry  6   7 , Amer Harky  8   9
Affiliations
Review

Aortic valve surgery: management and outcomes in the paediatric population

Mariam Zaidi et al. Eur J Pediatr. 2021 Oct.

Abstract

Congenital anomalies of the aortic valve frequently necessitate intervention in childhood. The most common aortic valve pathologies present in childhood are aortic stenosis and insufficiency. Presentation of aortic valve disease depends on severity and presence of concomitant syndromes and valvular disorders. Treatment options are largely categorised as medical, percutaneous repair or surgical repair and replacement. Surgical techniques have been refined over the last few years making this the mainstay of treatment in paediatric cases. Whilst repair is considered in most instances before replacement, there are substantial limitations which are reflected in the frequency of reintervention and restenosis rate. Replacements are typically undertaken with tissue or mechanical prosthesis. The current gold-standard aortic valve replacement surgery is called the Ross procedure-where replacement is undertaken with a competent pulmonic valve and a simultaneous pulmonary homograft.Conclusion: In this review, we aim to outline the various surgical options and discuss efficacy and complications of various interventions. What is Known: • Congenital aortic valve defects repair options medically and surgically What is New: • Comparisons between surgical options for aortic valve repair including efficacy, risks and long-term outcomes.

Keywords: Aorta; Congenital anomaly; Paediatric; Surgery.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Anatomy of the aortic valve (https://www.childrenshospital.org/conditions-and-treatments/conditions/a/aortic-valve-stenosis)
Fig. 2
Fig. 2
Parasternal long-axis view of neonatal critical aortic stenosis. A hypoplastic aortic valve annulus and post-stenotic dilation of the ascending aorta are noted
See this image and copyright information in PMC

References

    1. Rajamannan NM, Evans FJ, Aikawa E, Grande-Allen KJ, Demer LL, Heistad DD, Simmons CA, Masters KS, Mathieu P, O’Brien KD, et al. Calcific aortic valve disease: Not simply a degenerative process: a review and agenda for research from the National Heart and Lung and Blood Institute Aortic Stenosis Working Group. Executive summary: Calcific aortic valve disease-2011 update. Circulation. 2011;124:1783–1791. doi: 10.1161/CIRCULATIONAHA.110.006767. - DOI - PMC - PubMed
    1. Graffeo JM, Persaud HMS. Aortic regurgitation. J Am Acad Phys Assist. 2017;30(8):47–48. doi: 10.1097/01.JAA.0000521146.32701.24. - DOI - PubMed
    1. Mäkikallio K, McElhinney DB, Levine JC, et al. Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal intervention. Circulation. 2006;113(11):1401–1405. doi: 10.1161/CIRCULATIONAHA.105.588194. - DOI - PubMed
    1. Sugimoto A, Ota N, Miyakoshi C, Murata M, Ide Y, Tachi M, Ito H, Ogawa H, Sakamoto K. Mid- to long-term aortic valve-related outcomes after conventional repair for patients with interrupted aortic arch or coarctation of the aorta, combined with ventricular septal defect: the impact of bicuspid aortic valve†. Eur J Cardiothorac Surg. 2014;46(6):952–960. doi: 10.1093/ejcts/ezu078. - DOI - PubMed
    1. Frischhertz BP, Shamszad P, Pedroza C, Milewicz DM, Morris SA. Thoracic aortic dissection and rupture in conotruncal cardiac defects: a population-based study. Int J Cardiol. 2015;184:521–527. doi: 10.1016/j.ijcard.2015.03.061. - DOI - PubMed

LinkOut - more resources