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Comment
. 2021 May;27(5):763-764.
doi: 10.1038/s41591-021-01340-7.

Context matters in CAR T cell tonic signaling

Kristen Hege  1   2
Affiliations
Comment

Context matters in CAR T cell tonic signaling

Kristen Hege. Nat Med. 2021 May.
No abstract available

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Comment on

  • Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells.
    Singh N, Frey NV, Engels B, Barrett DM, Shestova O, Ravikumar P, Cummins KD, Lee YG, Pajarillo R, Chun I, Shyu A, Highfill SL, Price A, Zhao L, Peng L, Granda B, Ramones M, Lu XM, Christian DA, Perazzelli J, Lacey SF, Roy NH, Burkhardt JK, Colomb F, Damra M, Abdel-Mohsen M, Liu T, Liu D, Standley DM, Young RM, Brogdon JL, Grupp SA, June CH, Maude SL, Gill S, Ruella M. Singh N, et al. Nat Med. 2021 May;27(5):842-850. doi: 10.1038/s41591-021-01326-5. Epub 2021 Apr 22. Nat Med. 2021. PMID: 33888899 Free PMC article. Clinical Trial.

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    1. Singh, N. et al. Nat. Med. https://doi.org/10.1038/s41591-021-01326-5 (2021).

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